Depeiges A, Dacheux J L
J Reprod Fertil. 1985 May;74(1):23-7. doi: 10.1530/jrf.0.0740023.
Lizard spermatozoa, which are non-motile in the testis, develop the ability to swim as they pass along the excurrent duct. The addition of caffeine, a phosphodiesterase inhibitor, induced forward motility in spermatozoa from the caput epididymidis and increased the velocity of spermatozoa from the distal part of the epididymis. Caffeine had no effect on the motility of testicular spermatozoa. This suggests that sperm motility in this species is cyclic AMP-dependent but this factor alone is not sufficient to induce testicular sperm motility. In samples from the distal region of the epididymis, sperm motility was maximal in April just after the breeding season and then decreased significantly during the following months. A parallel can be drawn between these data and the levels of testosterone in the plasma. In the lizard, as in mammals, the epididymis may play an important role in the maturation of spermatozoa.
蜥蜴的精子在睾丸中不具有运动能力，但在通过输出管时会发育出游泳的能力。添加磷酸二酯酶抑制剂咖啡因可诱导附睾头精子产生向前运动，并提高附睾远端精子的速度。咖啡因对睾丸精子的运动没有影响。这表明该物种的精子运动依赖于环磷酸腺苷，但仅这一因素不足以诱导睾丸精子运动。在附睾远端区域的样本中，精子运动能力在繁殖季节刚结束后的4月达到最大值，随后在接下来的几个月中显著下降。这些数据与血浆中睾酮水平之间存在相似之处。与哺乳动物一样，在蜥蜴中，附睾可能在精子成熟过程中发挥重要作用。
