Newsholme S J, Cullen J S, Nel P W, Reyers F
J S Afr Vet Assoc. 1985 Jun;56(2):101-2.
An outbreak of a haemorrhagic syndrome involved recently weaned, mixed-breed pigs in a large piggery. The pigs were fed a pelleted complete ration containing antibacterial drugs. Affected pigs failed to grow, became pale and developed large, subcutaneous haematomas. Some pigs became lame and one had epistaxis. The monthly mortality rate in the weaner house, which was previously less than 2%, exceeded 6% during the outbreak. Coagulation time, activated partial thromboplastin time and prothrombin time were prolonged in blood from some of the pigs. The outbreak resolved promptly after supplementation of the diet with vitamin K3.
近期,一家大型养猪场中刚断奶的杂交猪爆发了一种出血综合征。这些猪食用的是含有抗菌药物的颗粒状全价日粮。患病猪生长停滞,变得苍白,并出现大面积皮下血肿。一些猪出现跛行,还有一头鼻出血。断奶仔猪舍此前每月死亡率低于2%,在疫情爆发期间超过了6%。部分病猪血液的凝血时间、活化部分凝血活酶时间和凝血酶原时间延长。日粮中补充维生素K3后,疫情迅速得到缓解。