Adolf Rafael, Ried Isabelle, Will Albrecht, Hendrich Eva, Bressem Keno, Engel Leif-Christoph, Hadamitzky Martin
Department of Radiology and Nuclear Medicine, German Heart Center Munich, TUM University Hospital, Institute for Cardiovascular Radiology and Nuclear Medicine, Lazarettstrasse 36, 80636, Munich, Germany.
Department of Cardiovascular Diseases, German Heart Center Munich, TUM University Hospital, Munich, Germany.
Int J Cardiovasc Imaging. 2025 Apr 10. doi: 10.1007/s10554-025-03392-z.
To evaluate whether different scan protocols using a first-generation dual-source photon-counting CT (PCD-CT) can reduce coronary stent artifacts and improve image quality in patients with chronic coronary artery disease (CAD) and in-stent restenosis (ISR).
Patients undergoing CCTA for suspected ISR or progression of CAD were consecutively enrolled between November 2021 and February 2023. Patients were scanned on a dual-source PCD-CT using standard acquisition mode with collimation of 144 × 0.4 mm or ultra-high-resolution (UHR) mode with collimation of 120 × 0.2 mm. Tube voltages were set at 120 or 140 kV. Scans were reconstructed using a standard kernel (Bv48), with UHR scans also reconstructed using a sharper kernel (Bv56).
A total of 25 patients were included in the study, of whom 80% were male, with a mean age of 68 ± 8 years (IQR 64.8-75.3). UHR mode, particularly with Bv56 kernels, provided significantly thinner vessel walls and reduced beam hardening artifacts compared to standard mode and Bv48 kernel, especially at lower tube voltages. Noise levels varied, with generally lower noise in UHR scans.
UHR mode with Bv56 kernels improves artifact reduction and vessel visualization in coronary stents, offering advantages over standard CCTA protocols. These findings may enhance the clinical diagnosis of ISR, leading to better patient outcomes through improved treatment planning.
评估使用第一代双源光子计数CT(PCD-CT)的不同扫描方案是否能减少慢性冠状动脉疾病(CAD)和支架内再狭窄(ISR)患者的冠状动脉支架伪影并提高图像质量。
2021年11月至2023年2月期间,连续纳入因疑似ISR或CAD进展而接受冠状动脉CT血管造影(CCTA)的患者。患者在双源PCD-CT上进行扫描,使用准直为144×0.4 mm的标准采集模式或准直为120×0.2 mm的超高分辨率(UHR)模式。管电压设置为120或140 kV。扫描使用标准内核(Bv48)进行重建,UHR扫描也使用更锐利的内核(Bv56)进行重建。
本研究共纳入25例患者,其中80%为男性,平均年龄为68±8岁(四分位距64.8 - 75.3)。与标准模式和Bv48内核相比,UHR模式,尤其是使用Bv56内核时,能提供明显更薄的血管壁并减少束硬化伪影,特别是在较低管电压下。噪声水平有所不同,UHR扫描中的噪声通常较低。
使用Bv56内核的UHR模式可改善冠状动脉支架的伪影减少和血管可视化,优于标准CCTA方案。这些发现可能会增强ISR的临床诊断,通过改进治疗计划带来更好的患者预后。