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老年重症患者气管切开术后死亡及长期预后的预测因素:一项回顾性分析

Predictive factors for death and long-term outcomes in elderly critically ill patients following tracheotomy: a retrospective analysis.

作者信息

Zhao Jingjing, Zhan Yuan, Chen Ting, Ling Gaoqiang, Fang Xiang, Yao Li

机构信息

Intensive Care Unit, Department of The Second People's Hospital of Hefei, Hefei Hospital Affiliated To Anhui Medical University, Hefei, No. 246 Heping Road, Anhui, 230011, China.

出版信息

BMC Anesthesiol. 2025 Apr 10;25(1):169. doi: 10.1186/s12871-025-03036-8.

Abstract

OBJECTIVE

To explore the factors influencing death in elderly critically ill patients within 3 months and 6 months after tracheotomy and to discuss the long-term quality of life of patients and the burden on caregivers by disease type.

METHODS

This retrospective study included 160 elderly patients with tracheostomies. The study aimed to analyze the risk factors associated with mortality at 3 and 6 months post-tracheotomy using both single-factor analysis and multifactor logistic regression. The subjects were categorized into three groups based on the type of disease. Kaplan-Meier survival curves and log-rank tests were utilized to assess differences in survival rates among these groups. Furthermore, the Personal Activities of Daily Living (PADL) scale, the SF- 12 scale, and the Zarit Burden Interview (ZBI) were administered to analyze and compare the quality of life among the patients.

RESULTS

The PSI score (95% CI: 1.008-1.036), total dose of vasoactive drugs (95% CI: 1.001-1.007), and the number of medical consultations (95% CI: 0.418-0.929,) were identified as independent risk factors for mortality within three months following tracheotomy in elderly patients. Additionally, the PSI score (95% CI: 1.001-1.026, P < 0.05) and the total dose of vasoactive drugs (95% CI: 1.001-1.007, P < 0.05) were also independent risk factors for patient death within six months. No significant differences were observed in the survival rates among the three subgroups followed up for six months, significant differences were noted in the PADL, ZBI, and SF- 12 scores among these subgroups.

CONCLUSION

The quality of life and risk factors for mortality within six months following tracheotomy in critically ill elderly patients warrant careful consideration. Caregivers face varying challenges due to different underlying conditions, particularly in cases involving severe pneumonia and cardiac insufficiency, which require increased social awareness.

摘要

目的

探讨老年重症患者气管切开术后3个月和6个月内影响死亡的因素,并按疾病类型探讨患者的长期生活质量及照顾者负担。

方法

本回顾性研究纳入160例老年气管切开患者。该研究旨在通过单因素分析和多因素逻辑回归分析气管切开术后3个月和6个月时与死亡率相关的危险因素。根据疾病类型将研究对象分为三组。采用Kaplan-Meier生存曲线和对数秩检验评估这些组之间生存率的差异。此外,使用日常生活能力(PADL)量表、SF-12量表和 Zarit照顾者负担访谈量表(ZBI)对患者的生活质量进行分析和比较。

结果

PSI评分(95%CI:1.008 - 1.036)、血管活性药物总剂量(95%CI:1.001 - 1.007)和会诊次数(95%CI:0.418 - 0.929)被确定为老年患者气管切开术后3个月内死亡的独立危险因素。此外,PSI评分(95%CI:1.001 - 1.026,P<0.05)和血管活性药物总剂量(95%CI:1.001 - 1.007,P<0.05)也是患者6个月内死亡的独立危险因素。随访6个月的三个亚组之间生存率无显著差异,但这些亚组之间的PADL、ZBI和SF - 12评分存在显著差异。

结论

重症老年患者气管切开术后6个月内的生活质量和死亡危险因素值得仔细考量。由于不同的基础疾病,照顾者面临不同的挑战,尤其是在涉及严重肺炎和心脏功能不全的情况下,这需要提高社会关注度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daa8/11984155/8c7ba12d1d08/12871_2025_3036_Fig1_HTML.jpg

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