Postnov I Iu, Liusov V A, Kazeev K N, Starkova N T
Kardiologiia. 1985 Apr;25(4):52-5.
Sodium permeability of erythrocyte membranes was examined, using the recording of maximum rates of sodium-lithium countertransport, in patients with essential hypertension of stages II and III by the WHO classification, renal arterial hypertension, Itsenko-Cushing disease, pheochromocytoma, Conn's syndrome and in subjects with normal arterial pressure who made up a control group. Hypertensive patients demonstrated a more than 60% increase in erythrocyte membrane permeability, as compared to normotensive controls. In patients with pheochromocytoma, the permeability values were almost 40% as low as the control ones. No changes in sodium erythrocyte membrane permeability could be demonstrated in patients with renal hypertension, Itsenko-Cushing disease and Conn's syndrome. It is believed that the erythrocyte membrane permeability parameters can be used for the identification of essential hypertension in the differential diagnosis of hypertensions.
采用钠-锂逆向转运最大速率记录法，对世界卫生组织分类的Ⅱ期和Ⅲ期原发性高血压患者、肾动脉性高血压患者、库欣病患者、嗜铬细胞瘤患者、康恩综合征患者以及作为对照组的血压正常者的红细胞膜钠通透性进行了检测。与血压正常的对照组相比，高血压患者的红细胞膜通透性增加了60%以上。嗜铬细胞瘤患者的通透性值几乎比对照组低40%。肾性高血压患者、库欣病患者和康恩综合征患者的红细胞膜钠通透性未显示出变化。据信，红细胞膜通透性参数可用于在高血压的鉴别诊断中识别原发性高血压。
