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颈椎骨外尤文肉瘤:一例报告。

Cervical extraosseous Ewing's sarcoma: A case report.

作者信息

Chitsaz Ahmad, Etemadifar Masoud, Fallahpour Soheil, Riazi Ali, Askariardehjani Navid, Ameri Mohammadmehdi

机构信息

Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Radiol Case Rep. 2025 Mar 24;20(6):2946-2949. doi: 10.1016/j.radcr.2025.02.093. eCollection 2025 Jun.

Abstract

Ewing's sarcoma itself is an uncommon disease. But its occurrence as a primary extraosseous cervical lesion is extremely rare. Considering the rarity of the manifestation of this disease in the form of a soft tissue mass in the neck, and the occurrence with nonspecific initial symptoms, this study introduces a patient whose only initial symptom was neck pain. The patient was a 23-year-old man who had been suffering from neck pain for ten days. Due to neck pain and 1 episode of urinary incontinence, the patient was hospitalized and examined. In the first 6 hours after admission, the patient experienced weakness of the upper limbs. A round lesion was seen in the alignment of the second vertebra with dimensions of 7 × 6 cm. Due to the progression of clinical symptoms, especially in the upper limbs, emergency surgery was planned for the patient. The diagnosis was Ewing's carcinoma. Tumoral cells were seen in diffuse form in small size with large nuclei, hyperchromatic and high N/C with large areas of necrosis. In conclusion, the urgency of surgical intervention in extraosseous Ewing sarcoma cannot be overstated, and it is essential for healthcare providers to remain vigilant in recognizing the signs of this aggressive disease to facilitate timely and effective treatment.

摘要

尤因肉瘤本身是一种罕见疾病。但其作为原发性骨外颈部病变的情况极为罕见。鉴于这种疾病以颈部软组织肿块形式表现的罕见性,以及其初始症状不具特异性,本研究介绍了一位仅以颈部疼痛为初始症状的患者。该患者为一名23岁男性,颈部疼痛已持续十天。因颈部疼痛及一次尿失禁,患者入院接受检查。入院后的前6小时,患者出现上肢无力。在第二颈椎水平可见一个圆形病变,大小为7×6厘米。由于临床症状进展,尤其是上肢症状,为患者计划了急诊手术。诊断为尤因癌。肿瘤细胞呈弥漫性,体积小,核大,染色质深,核质比高,并有大片坏死区域。总之,对于骨外尤因肉瘤,手术干预的紧迫性再怎么强调都不为过,医疗服务提供者必须保持警惕,识别这种侵袭性疾病的体征,以便及时进行有效治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a0/11985035/d0a1117de74a/gr1.jpg

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