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单纯先天性和腱膜性上睑下垂中“闭合式提上睑肌后徙术”的比较评估

Comparative evaluation of "closed posterior levator advancement" in simple congenital and aponeurotic ptosis.

作者信息

Goel Ruchi, Singh Sonam, Shah Shalin, Khanam Samreen, Golhait Priyanka, Gaonker Tanvi

机构信息

Department of Ophthalmology, Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.

出版信息

Taiwan J Ophthalmol. 2024 Jan 5;15(1):120-125. doi: 10.4103/tjo.TJO-D-23-00081. eCollection 2025 Jan-Mar.

Abstract

PURPOSE

The purpose of this study was to compare the outcomes of "closed posterior levator advancement" (CPLA) in acquired aponeurotic and simple congenital ptosis with good levator function (LF).

MATERIALS AND METHODS

A prospective interventional study was conducted on 20 adult patients, 10 simple congenital ptosis, and 10 acquired aponeurotic ptosis with LF ≥8 mm. Complicated, posttraumatic, neurogenic ptosis and previous lid surgery were excluded. A detailed history and assessment of visual acuity, upper eyelid margin reflex distance (MRD1), margin-crease distance, LF, Bell's phenomenon, ocular surface disease index (OSDI), and phenylephrine test were undertaken. CPLA was performed in the 20 eyes and were followed up for 3 months.

RESULTS

The ages of the study participants ranged from 18 to 64 years, and the male: female ratio was 11:9. There were nine aponeurotic and one congenital severe ptosis, the remaining 10 being mild-moderate ptosis. The etiologies in the aponeurotic group were involutional (2), contact lens wear (1), allergic conjunctivitis (3), and idiopathic in four eyes. The success rates were 90% in both groups. The amount of ptosis correction showed a positive relation with LF ( = 0.6, = 0.004) and phenylephrine test ( = 0.7, < 0.001). The complications in the aponeurotic group were lagophthalmos (2/10), subjective dry eye (2/10), subconjunctival hemorrhage (1/10), symblepharon (1/10), temporal flare (1/10), and overcorrection (1/10). The congenital group showed only undercorrection (1/10).

CONCLUSION

CPLA is an effective procedure for the treatment of mild-moderate simple congenital and all grades of aponeurotic ptosis with good LF. Response to phenylephrine test serves as a useful guide to the amount of ptosis correction.

摘要

目的

本研究旨在比较“闭合式提上睑肌后徙术”(CPLA)治疗获得性腱膜性上睑下垂和单纯先天性上睑下垂且提上睑肌功能(LF)良好的疗效。

材料与方法

对20例成年患者进行前瞻性干预研究,其中10例为单纯先天性上睑下垂,10例为获得性腱膜性上睑下垂,LF≥8mm。排除复杂性、创伤后、神经源性上睑下垂及既往眼睑手术史患者。详细记录病史,并评估视力、上睑缘反射距离(MRD1)、睑缘-皱襞距离、LF、贝尔现象、眼表疾病指数(OSDI)及去氧肾上腺素试验。对20只眼行CPLA手术,并随访3个月。

结果

研究参与者年龄在18至64岁之间,男女比例为11:9。腱膜性上睑下垂9例,先天性重度上睑下垂1例,其余10例为轻中度上睑下垂。腱膜性上睑下垂组的病因包括退行性变(2例)、佩戴隐形眼镜(1例)、过敏性结膜炎(3例),4例病因不明。两组成功率均为90%。上睑下垂矫正量与LF(r = 0.6,P = 0.004)及去氧肾上腺素试验(r = 0.7,P < 0.001)呈正相关。腱膜性上睑下垂组的并发症包括兔眼(2/10)、主观干眼(2/10)、结膜下出血(1/10)、睑球粘连(1/10)、颞侧闪光感(1/10)及矫正过度(1/10)。先天性上睑下垂组仅出现矫正不足(1/10)。

结论

CPLA是治疗轻中度单纯先天性上睑下垂及所有程度腱膜性上睑下垂且LF良好的有效方法。去氧肾上腺素试验结果可作为上睑下垂矫正量的有用指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55f7/11981559/08822b7667a7/TJO-15-120-g001.jpg

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