Ma Shang-Te, Lin Yueh-Shen, Liao Shu-Lang, Wei Yi-Hsuan
Department of Ophthalmology, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare, New Taipei City, Taiwan.
Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Taiwan J Ophthalmol. 2023 Jun 16;15(1):143-146. doi: 10.4103/tjo.TJO-D-23-00016. eCollection 2025 Jan-Mar.
A 29-year-old woman experienced long-term phthisis bulbi owing to previous refractory idiopathic posterior uveitis since childhood and eventually underwent evisceration. Histological examination revealed that the retina was intermingled with the unusual glial mass lesion, which contained spindle cells with the elongated fibrillary process and columnar cells surrounding the round lumen with pseudorosettes formation. Mitoses were rarely seen. The tumor cells expressed S100, glial fibrillary acidic protein, CD99, and vimentin, while Ki67 was not detected. The final diagnosis was intraocular retinal ependymoma. Intraocular ependymoma was extremely rare and lacked comprehensive literature reviews. Our case is the very first example of retinal ependymoma in East Asia. Evisceration or enucleation followed by regular scrutinization is regarded sufficient for treating this condition.
一名29岁女性因自幼患有难治性特发性后葡萄膜炎而长期患眼球痨，最终接受了眼内容剜除术。组织学检查发现视网膜与异常的胶质肿块病变混合，该病变包含具有细长纤维状突起的梭形细胞和围绕圆形管腔并形成假菊形团的柱状细胞。很少见到有丝分裂。肿瘤细胞表达S100、胶质纤维酸性蛋白、CD99和波形蛋白，而未检测到Ki67。最终诊断为眼内视网膜室管膜瘤。眼内室管膜瘤极为罕见，且缺乏全面的文献综述。我们的病例是东亚地区首例视网膜室管膜瘤。眼内容剜除术或眼球摘除术并定期复查被认为足以治疗这种疾病。
