在已知产生λ链的小鼠骨髓瘤MOPC-104E中存在κ和λ轻链信使RNA序列。 - Suppr | 超能文献

Existence of both kappa and lambda light chain messenger RNA sequences in mouse myeloma, MOPC-104E, known as a lambda chain producer.

作者信息

Ono M, Kawakami M

出版信息

Biochem Biophys Res Commun. 1977 Jan 24;74(2):796-802. doi: 10.1016/0006-291x(77)90373-4.

DOI:10.1016/0006-291x(77)90373-4

Abstract

摘要

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Existence of both kappa and lambda light chain messenger RNA sequences in mouse myeloma, MOPC-104E, known as a lambda chain producer.在已知产生λ链的小鼠骨髓瘤MOPC-104E中存在κ和λ轻链信使RNA序列。

Biochem Biophys Res Commun. 1977 Jan 24;74(2):796-802. doi: 10.1016/0006-291x(77)90373-4.

2

Untranslated immunoglobulin kappa light chain mRNA in a lambda light chain-producing mouse myeloma, MOPC104E.在产生λ轻链的小鼠骨髓瘤MOPC104E中未翻译的免疫球蛋白κ轻链mRNA。

J Biol Chem. 1980 Jun 10;255(11):5291-5.

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Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain.产生单一功能性轻链的小鼠骨髓瘤细胞中多个轻链基因的活性

Cell. 1980 Aug;21(1):1-12. doi: 10.1016/0092-8674(80)90109-9.

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Purification and translation of an immunoglobulin lambda chain messenger RNA from mouse myeloma.从小鼠骨髓瘤中纯化和翻译免疫球蛋白λ链信使核糖核酸

Biochemistry. 1976 Jun 29;15(13):2775-9. doi: 10.1021/bi00658a011.

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Amino acid sequence of the NH2-terminal extra piece segments of the precursors of mouse immunoglobulin lambda1-type and kappa-type light chains.小鼠免疫球蛋白λ1型和κ型轻链前体的NH2末端额外片段的氨基酸序列。

Proc Natl Acad Sci U S A. 1977 Feb;74(2):716-20. doi: 10.1073/pnas.74.2.716.

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Glutamine as a precursor to N-terminal pyrrolid-2-one-5-carboxylic acid in mouse immunoglobulin lambda-type light chains. Amino acid-sequence variability at the N-terminal extra piece of lambda-type light-chain precursors.谷氨酰胺作为小鼠免疫球蛋白λ型轻链中N端吡咯烷-2-酮-5-羧酸的前体。λ型轻链前体N端额外片段的氨基酸序列变异性。

Biochem J. 1977 Aug 1;165(2):347-54. doi: 10.1042/bj1650347.

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Arrangement of lambda light chain genes in mutant clones of the MOPC 315 mouse myeloma cells.MOPC 315小鼠骨髓瘤细胞突变克隆中λ轻链基因的排列

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Quantitation of constant and variable region genes for mouse immunoglobulin lambda chains.小鼠免疫球蛋白λ链恒定区和可变区基因的定量分析

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Transcription in vitro of immunoglobulin kappa light chain genes in isolated mouse myeloma nuclei and chromatin.在分离的小鼠骨髓瘤细胞核和染色质中进行免疫球蛋白κ轻链基因的体外转录。

Proc Natl Acad Sci U S A. 1976 Mar;73(3):775-9. doi: 10.1073/pnas.73.3.775.

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Reiteration frequency of immunoglobulin light chain genes: further evidence for somatic generation of antibody diversity.免疫球蛋白轻链基因的重复频率：抗体多样性体细胞产生的进一步证据。

Proc Natl Acad Sci U S A. 1976 Jan;73(1):203-7. doi: 10.1073/pnas.73.1.203.

引用本文的文献

1

Immunoglobulin gene expression in a coupled transcription/translation system from mouse plasmacytoma cell-free extracts.小鼠浆细胞瘤无细胞提取物偶联转录/翻译系统中的免疫球蛋白基因表达。

Biochem Genet. 1981 Dec;19(11-12):1183-209. doi: 10.1007/BF00484573.

2

Unrearranged immunoglobulin lambda variable region is transcribed in kappa-producing myelomas.未重排的免疫球蛋白λ可变区在产生κ链的骨髓瘤中被转录。

EMBO J. 1984 Dec 1;3(12):3031-5. doi: 10.1002/j.1460-2075.1984.tb02250.x.