Weber U, Goerz G, Hennekes R
Klin Monbl Augenheilkd. 1985 May;186(5):351-4. doi: 10.1055/s-2008-1050936.
Thirty patients who had undergone long-term treatment with carotenoids (max. 14 years and 336 g of carotenoids) were examined. Ophthalmoscopy revealed retinal crystals in 20 patients. The retinal crystals were usually located around the macula, forming a ring, and in one case they were even found in the macula itself. No deterioration of visual acuity or visual field defects were found, but there was a markedly dose-dependent prolongation of the duration of dark adaptation.
对30名接受类胡萝卜素长期治疗（最长14年，摄入类胡萝卜素336克）的患者进行了检查。检眼镜检查发现20名患者有视网膜晶体。视网膜晶体通常位于黄斑周围，形成一个环，在1例患者中甚至在黄斑本身发现了晶体。未发现视力下降或视野缺损，但暗适应持续时间有明显的剂量依赖性延长。
