Goldsworthy Adrian, Shiratuddin Mohd Fairuz, Tronstad Oystein, Fraser John F, Olsen Matthew, Tajouri Lotti, Wong Kok Wai
Wesley Research Institute, Brisbane, Australia; The Prince Charles Hospital Critical Care Research Group, Brisbane, Australia; Murdoch University, School of Information Technology, Perth, Western Australia, Australia; Bond University, Faculty of Health Sciences and Medicine, Gold Coast, Australia.
Murdoch University, School of Information Technology, Perth, Western Australia, Australia.
Aust Crit Care. 2025 Jul;38(4):101231. doi: 10.1016/j.aucc.2025.101231. Epub 2025 Apr 10.
The objective of this research was to investigate if the use of virtual reality, increasingly utilised within intensive care medicine due to its demonstrated benefits in improving pain and anxiety, has been reported to result in seizures.
A rapid systematic review and synthesis of qualitative and quantitative data was performed.
Five databases (PubMed, Scopus, EMBASE, PsycInfo, and CINAHL) were systematically searched. An additional gray literature search was also conducted. Articles were restricted to those published on or after January 1st, 2014.
The number of participants, virtual reality sessions, and length of sessions was undertaken. Subgroup analysis was undertaken for both adult and paediatric patient populations. An additional subgroup analysis was undertaken on articles which did not exclude individuals with a history of epilepsy. A tailored risk-of-bias assessment was conducted.
Of the 563 articles identified through database and gray literature searching, 27 articles met inclusion criteria. A total of 886 patients have been reported within the literature with a combined 1843 virtual reality sessions, totalling more than 614.64 h of virtual reality. No seizures have been reported within intensive care patients receiving virtual reality interventions.
Historically, individuals with a history of epilepsy and photosensitivity have been commonly excluded from interventions and clinical trials involving virtual reality. The results of this systematic review demonstrate that the risk of virtual reality is minimal when utilised appropriately. A history of photosensitivity or epilepsy should not constitute an absolute contraindication for the use of virtual reality. Instead, clinicians should utilise clinical judgement when evaluating a patient's risk and ensure that appropriate visual experiences are utilised which do not unnecessarily strobe the patient.
本研究的目的是调查虚拟现实技术在重症监护医学中因在改善疼痛和焦虑方面显示出的益处而越来越多地被使用，是否有报道称其会导致癫痫发作。
对定性和定量数据进行了快速系统综述和综合分析。
系统检索了五个数据库（PubMed、Scopus、EMBASE、PsycInfo和CINAHL）。还进行了额外的灰色文献检索。文章限于2014年1月1日及以后发表的文献。
统计了参与者数量、虚拟现实治疗次数和治疗时长。对成人和儿童患者群体进行了亚组分析。对未排除有癫痫病史个体的文章进行了额外的亚组分析。进行了针对性的偏倚风险评估。
通过数据库和灰色文献检索确定的563篇文章中，有27篇符合纳入标准。文献中共报道了886例患者，共进行了1843次虚拟现实治疗，虚拟现实总时长超过614.64小时。接受虚拟现实干预的重症监护患者中未报告癫痫发作。
历史上，有癫痫病史和光敏性的个体通常被排除在涉及虚拟现实的干预措施和临床试验之外。本系统综述的结果表明，适当使用虚拟现实时风险极小。光敏性或癫痫病史不应构成使用虚拟现实的绝对禁忌证。相反，临床医生在评估患者风险时应运用临床判断，并确保使用适当的视觉体验，避免不必要地对患者造成频闪刺激。
