Dynamic monitoring and multi-pathway regulation of FBXO21 in renal clear cell carcinoma: from static marker to perspective of precision therapy.
作者信息
Long Jiaorong
机构信息
Department of Nephrology, Beilun People's Hospital, Ningbo, 315800, Zhejiang, China.
出版信息
J Transl Med. 2025 Apr 11;23(1):429. doi: 10.1186/s12967-025-06411-8.
Abstract
摘要
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本文引用的文献
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Single-cell RNA sequencing and spatial transcriptomics reveal the heterogeneity and intercellular communication of cancer-associated fibroblasts in gastric cancer.单细胞RNA测序和空间转录组学揭示了胃癌中癌症相关成纤维细胞的异质性和细胞间通讯。
J Transl Med. 2025 Mar 18;23(1):344. doi: 10.1186/s12967-025-06376-8.
2
F-box protein FBXO21 overexpression inhibits the proliferation and metastasis of clear cell renal cell carcinoma and is closely related to the CREB pathway and tumor immune cell infiltration.F-box蛋白FBXO21的过表达抑制透明细胞肾细胞癌的增殖和转移，并与CREB通路及肿瘤免疫细胞浸润密切相关。
J Transl Med. 2025 Mar 15;23(1):335. doi: 10.1186/s12967-025-06356-y.
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Spatial oncology: Translating contextual biology to the clinic.空间肿瘤学：将上下文生物学转化为临床实践。
Cancer Cell. 2024 Oct 14;42(10):1653-1675. doi: 10.1016/j.ccell.2024.09.001. Epub 2024 Oct 3.
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PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathway.PLAUR 通过激活 PI3K/AKT/mTOR 信号通路促进肾透明细胞癌的进展。
PeerJ. 2024 Jun 27;12:e17555. doi: 10.7717/peerj.17555. eCollection 2024.
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Prognostic significance of PI3K/AKT/ mTOR signaling pathway members in clear cell renal cell carcinoma.PI3K/AKT/mTOR信号通路成员在透明细胞肾细胞癌中的预后意义
PeerJ. 2020 Jun 1;8:e9261. doi: 10.7717/peerj.9261. eCollection 2020.
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