Kidokoro Tetsuhiro, Kitano Naruki, Imai Natsuko, Lang Justin J, Tomkinson Grant R, Magnussen Costan G
Faculty of Sport Science, Nippon Sport Science University, 7-1-1, Fukasawa, Setagaya, Tokyo, 158-8508, Japan.
Alliance for Research in Exercise, Nutrition and Activity (ARENA), University of South Australia, Adelaide, SA, Australia.
J Act Sedentary Sleep Behav. 2023 Oct 3;2(1):20. doi: 10.1186/s44167-023-00029-1.
Optimizing childhood domain-specific physical activity (PA) and sedentary behavior (SB) for blood lipid profile is not well understood. We aimed to (1) determine the associations between accelerometer-measured PA and SB for each domain (school time and out-of-school time) with blood lipid profile and (2) estimate predicted changes in blood lipid profile with hypothetical time-reallocation between domain-specific SB and PA among Japanese children using compositional data analysis (CoDA).
This cross-sectional study included 284 children (147 boys and 137 girls) aged 9-12 years (mean age [years]: 10.1 ± 1.2 for boys, 10.0 ± 1.1 for girls; mean body mass index: 18.2 ± 3.2 for boys, 17.5 ± 2.5 for girls). Time spent in domain-specific SB, light-intensity PA (LPA), moderate-intensity PA (MPA), and vigorous-intensity PA (VPA) was assessed using accelerometry. The non-fasting lipid profile considered measures of triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and non-HDL-C levels. CoDA and isotemporal substitution model were performed to examine the associations of domain-specific PA and SB with blood lipids.
Time spent in out-of-school VPA relative to the other behaviors was negatively associated with non-HDL-C (boys: β = - 0.10, 95% confidence interval [CI] = - 0.19 to - 0.01), TG (boys: β = - 0.45, 95% CI = - 0.68 to - 0.22), and positively associated with HDL-C (girls: β = 0.09, 95% CI = 0.02 to 0.16) after adjusting for age, body mass index, and time spent in SB, LPA, and MPA. During the out-of-school period, a replacement of 1 min of any other behavior with VPA was associated with decreases in LDL-C in boys (predicted changes [95% CI] - 0.03 mmol/L [- 0.05 to - 0.00] for LPA), non-HDL-C in boys (predicted changes [95% CI] - 0.03 mmol/L [- 0.06 to - 0.01] for SB and LPA) and TG in boys (predicted changes [95% CI] - 0.04 mmol/L [- 0.06 to - 0.02] for SB and LPA, - 0.05 mmol/L [- 0.07 to - 0.02] for MPA) and in girls (predicted changes [95% CI] - 0.02 mmol/L [- 0.04 to - 0.00] for LPA), and increases in HDL-C in girls (predicted changes [95% CI] 0.02 mmol/L [0.00 to 0.04] for SB and LPA, 0.03 mmol/L [0.00 to 0.05] for MPA).
Increasing out-of-school VPA might be an effective approach to improve blood lipid profiles among Japanese children.
对于优化儿童特定领域的身体活动（PA）和久坐行为（SB）以改善血脂水平，我们还了解得不够。我们旨在：（1）确定通过加速度计测量的每个领域（上学时间和校外时间）的PA和SB与血脂水平之间的关联；（2）使用成分数据分析（CoDA），估计日本儿童在特定领域的SB和PA之间进行假设性时间重新分配后血脂水平的预测变化。
这项横断面研究纳入了284名9至12岁的儿童（147名男孩和137名女孩）（男孩平均年龄[岁]：10.1±1.2，女孩10.0±1.1；男孩平均体重指数：18.2±3.2，女孩17.5±2.5）。使用加速度计评估在特定领域的SB、轻度PA（LPA）、中度PA（MPA）和剧烈PA（VPA）上花费的时间。非空腹血脂水平包括甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）和非HDL-C水平的测量。采用CoDA和等时替代模型来研究特定领域的PA和SB与血脂之间的关联。
在校外VPA上花费的时间相对于其他行为，在调整年龄、体重指数以及在SB、LPA和MPA上花费的时间后，与男孩的非HDL-C呈负相关（β=-0.10，95%置信区间[CI]=-0.19至-0.01）、TG呈负相关（男孩：β=-0.45，95%CI=-0.68至-0.22），与女孩的HDL-C呈正相关（β=0.09，95%CI=0.02至0.16）。在校外期间，男孩用1分钟VPA替代任何其他行为与LDL-C降低相关（LPA的预测变化[95%CI]-0.03mmol/L[-0.05至-0.00]）、男孩的非HDL-C降低相关（SB和LPA的预测变化[95%CI]-0.03mmol/L[-0.06至-0.01]）以及男孩的TG降低相关（SB和LPA的预测变化[95%CI]-0.04mmol/L[-0.06至-0.02]，MPA的预测变化[95%CI]-0.05mmol/L[-0.07至-0.02]），女孩的LPA与LDL-C降低相关（预测变化[95%CI]-0.02mmol/L[-0.04至-0.00]），女孩用1分钟VPA替代任何其他行为与HDL-C升高相关（SB和LPA的预测变化[95%CI]0.02mmol/L[0.00至0.04]，MPA的预测变化[95%CI]0.03mmol/L[0.00至0.05]）。
增加校外VPA可能是改善日本儿童血脂水平的有效方法。
