[Radionuclide and macro-microangiographic study of pulmonary ventilation and blood flow in chronic nonspecific lung diseases].

A study was made of ventilation and perfusion in 105 patients with chronic pulmonary nonspecific diseases using radiopneumography with 133Xe. A simultaneous macro-microangiographic study was made of the pulmonary artery on specimens taken after lobectomy in 35 patients with bronchiectasia in the lower lobe. The control group was composed of 35 specimens of the healthy lungs taken from unembalmed cadavers of people who died of diseases unrelated to the involvement of the respiratory system as well as from 30 healthy people after radiopneumography. Asymmetry of the distribution of ventilation and perfusion is typical of patients with bronchiectasia. It manifests itself in a significant decrease in the VLC and the blood flow in the affected zone. A simultaneous compensatory rise of perfusion was recorded. In a macro-microangiographic study a rough deformity of the vascular trunks at the level of the segmental and subsegmental vessels was marked in these patients; angles of the outgoing of vessels of the main trunk decreased significantly, the number of vessels with a winding course increased. Simultaneous anatomostructural radionuclide studies make it possible to understand more deeply the essence of a pathological process.