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[肺动脉压力升高在支气管阻塞时灌注分布及气体交换中的作用]

[Role of the rise of pressure in the pulmonary artery in the distribution of perfusion and gas exchange in bronchial obstruction].

作者信息

Putov N V, Danilov L N, Lebedeva E S, Egurnov N I, Kuznetsova V K

出版信息

Biull Eksp Biol Med. 1989 Jan;107(1):8-10.

PMID:2914178
Abstract

The experiments on the dogs revealed that the damage of lobar bronchus conduction resulted in the decrease of O2 tension in pulmonary venous blood of this lobe. The decrease in the ventilation and blood flow was found in the zone of obstruction by using tracers 133Xe and 99mTc. The pressure rise in the pulmonary artery caused by the spread of bronchial obstruction is one of the factors promoting the redistribution of perfusion into the reserve zones of lungs. The decrease of pressure by the ganglio-blocking preparation results in the increase of arterial hypoxemia.

摘要

对狗的实验表明,叶支气管传导受损会导致该叶肺静脉血中氧分压降低。通过使用示踪剂133Xe和99mTc发现,在阻塞区域存在通气和血流减少的情况。支气管阻塞蔓延导致的肺动脉压力升高是促使灌注重新分布到肺储备区的因素之一。神经节阻断制剂导致的压力降低会使动脉低氧血症加重。

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