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直肠癌治疗中的共同决策

Shared Decision Making in the Treatment of Rectal Cancer.

作者信息

Abelson Jonathan S, Gaetani Racquel S, Hawkins Alexander T

机构信息

Department of Colorectal Surgery, Lahey Hospital and Medical Center, Burlington, MA 01805, USA.

Section of Colorectal Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

出版信息

J Clin Med. 2025 Mar 26;14(7):2255. doi: 10.3390/jcm14072255.

DOI:10.3390/jcm14072255
PMID:40217705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11989943/
Abstract

: The management of locally advanced rectal cancer has evolved significantly, shaped by advances in multimodal neoadjuvant therapy and a growing emphasis on organ preservation through the watch-and-wait approach. These advancements, however, introduce complex treatment decisions that require careful consideration by both patients and clinicians. : This narrative review explores the evolution of the management of locally advanced rectal cancer and the role of shared decision-making in guiding treatment decisions, particularly for patients facing decisions between surgical resection and watch-and-wait. Additionally, it discusses the development of tools to aid in shared-decision making, current challenges in implementing shared decision-making and future directions for improvement patient centered care in locally advanced rectal cancer management. : Considerations for decision making include anatomical considerations that influence surgical options, the potential benefits and risks of watch-and-wait versus surgical resection of the rectum, and the impact of treatment on bowel, urinary, and sexual function. Additionally, patients must weigh the long-term implications of their choices on quality of life. : Shared decision-making has emerged as a critical component of patient-centered care and ensures that treatment decisions align with patients' values and priorities. Given the preference-sensitive nature of the management of locally advanced rectal cancer, shared decision-making plays an important role in helping patients navigate these decisions.

摘要

局部晚期直肠癌的治疗管理已经发生了显著演变,这受到多模式新辅助治疗进展以及通过观察等待方法对器官保留日益重视的影响。然而,这些进展带来了复杂的治疗决策,需要患者和临床医生仔细考虑。

本叙述性综述探讨了局部晚期直肠癌治疗管理的演变以及共同决策在指导治疗决策中的作用,特别是对于面临手术切除和观察等待之间决策的患者。此外,它还讨论了有助于共同决策的工具的发展、实施共同决策当前面临的挑战以及在局部晚期直肠癌管理中改善以患者为中心的护理的未来方向。

决策考量包括影响手术选择的解剖学因素、观察等待与直肠手术切除的潜在益处和风险,以及治疗对肠道、泌尿和性功能的影响。此外,患者必须权衡其选择对生活质量的长期影响。

共同决策已成为以患者为中心的护理的关键组成部分,并确保治疗决策与患者的价值观和优先事项相一致。鉴于局部晚期直肠癌治疗管理的偏好敏感性,共同决策在帮助患者应对这些决策方面发挥着重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b3/11989943/07d81e84a10d/jcm-14-02255-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b3/11989943/d6b590b024bc/jcm-14-02255-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b3/11989943/07d81e84a10d/jcm-14-02255-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b3/11989943/d6b590b024bc/jcm-14-02255-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40b3/11989943/07d81e84a10d/jcm-14-02255-g002.jpg

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本文引用的文献

1
Therapeutic Management of Locally Advanced Rectal Cancer: Existing and Prospective Approaches.局部进展期直肠癌的治疗管理:现有方法与前瞻性方法
J Clin Med. 2025 Jan 30;14(3):912. doi: 10.3390/jcm14030912.
2
What Predicts Complete Response to Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer?什么因素能预测局部晚期直肠癌对新辅助治疗的完全缓解?
Dis Colon Rectum. 2025 Jan 1;68(1):60-68. doi: 10.1097/DCR.0000000000003395. Epub 2024 Sep 11.
3
Decision Aid for Colectomy in Recurrent Diverticulitis: Development and Usability Study.
在复发性憩室炎中进行结肠切除术的决策辅助:开发和可用性研究。
JMIR Form Res. 2024 Sep 3;8:e59952. doi: 10.2196/59952.
4
Journey through the Decades: The Evolution in Treatment and Shared Decision Making for Locally Advanced Rectal Cancer.数十年历程:局部晚期直肠癌治疗与共同决策的演变
Cancers (Basel). 2024 Aug 9;16(16):2807. doi: 10.3390/cancers16162807.
5
Past, Present, and Future of Shared Decision-Making.共同决策的过去、现在与未来。
Circ Cardiovasc Qual Outcomes. 2024 Jul;17(7):e010584. doi: 10.1161/CIRCOUTCOMES.124.010584. Epub 2024 Jul 16.
6
Artificial Intelligence Applications in the Treatment of Colorectal Cancer: A Narrative Review.人工智能在结直肠癌治疗中的应用:一篇综述
Clin Med Insights Oncol. 2024 Jan 5;18:11795549231220320. doi: 10.1177/11795549231220320. eCollection 2024.
7
A Qualitative Exploration of Stakeholders' Preferences for Early-Stage Rectal Cancer Treatment.利益相关者对早期直肠癌治疗偏好的定性探索
Ann Surg Open. 2023 Dec 14;4(4):e364. doi: 10.1097/AS9.0000000000000364. eCollection 2023 Dec.
8
Practice Patterns for Organ Preservation in US Patients With Rectal Cancer, 2006-2020.2006 - 2020年美国直肠癌患者器官保留的实践模式
JAMA Oncol. 2024 Jan 1;10(1):79-86. doi: 10.1001/jamaoncol.2023.4845.
9
The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Rectal Cancer 2023 Supplement.美国结肠和直肠外科医师协会《2023年直肠癌管理临床实践指南补充版》
Dis Colon Rectum. 2024 Jan 1;67(1):18-31. doi: 10.1097/DCR.0000000000003057. Epub 2023 Aug 20.
10
Shared Decision-Making in the Surgical Sciences.外科学领域的共同决策
JAMA Surg. 2023 Nov 1;158(11):1121-1122. doi: 10.1001/jamasurg.2023.2396.