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蘑菇状穿透性角膜移植术:一篇叙述性综述

Mushroom Penetrating Keratoplasty: A Narrative Review.

作者信息

Bergamaschi Pietro, Busin Linda Marie Louise, Yu Angeli Christy, Busin Massimo

机构信息

Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.

Department of Ophthalmology, Ospedali Privati Forlì, 47121 Forli, Italy.

出版信息

J Clin Med. 2025 Mar 29;14(7):2351. doi: 10.3390/jcm14072351.

DOI:10.3390/jcm14072351
PMID:40217814
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11989387/
Abstract

While full-thickness penetrating keratoplasty (PK) has seen a decline in favor of partial-thickness techniques like endothelial keratoplasty (EK) and anterior lamellar keratoplasty (ALK), PK remains indicated for corneal disease involving the entire corneal thickness. Mushroom keratoplasty (MK) is a noteworthy modification of PK, designed to combine the refractive benefits of a large-diameter anterior lamellar graft with the graft survival advantage of limited replacement of the corneal endothelium. Leveraging the use of a microkeratome, the MK donor graft can be prepared by microkeratome dissection, thereby achieving a central interface compatible with 20/20 Snellen vision. This review explores the various surgical techniques, visual outcomes, graft survival rates, and complication rates associated with MK for various indications.

摘要

虽然全层穿透性角膜移植术(PK)已不如内皮角膜移植术(EK)和前板层角膜移植术(ALK)等部分厚度技术受欢迎,但PK仍适用于累及整个角膜厚度的角膜疾病。蘑菇状角膜移植术(MK)是PK的一种值得注意的改良术式,旨在将大直径前板层移植物的屈光优势与有限替换角膜内皮的移植物存活优势相结合。利用微型角膜刀,MK供体移植物可通过微型角膜刀切割制备,从而实现与20/20斯内伦视力相兼容的中央界面。本综述探讨了与MK用于各种适应症相关的各种手术技术、视觉效果、移植物存活率和并发症发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/010e/11989387/abffefa2a865/jcm-14-02351-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/010e/11989387/9f1ec6301eae/jcm-14-02351-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/010e/11989387/abffefa2a865/jcm-14-02351-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/010e/11989387/9f1ec6301eae/jcm-14-02351-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/010e/11989387/abffefa2a865/jcm-14-02351-g002.jpg

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Large-diameter deep anterior lamellar keratoplasty: A narrative review.大直径深前板层角膜移植术:一项叙述性综述。
Taiwan J Ophthalmol. 2024 Feb 23;14(1):27-33. doi: 10.4103/tjo.TJO-D-23-00161. eCollection 2024 Jan-Mar.
3
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大直径深前板层角膜移植术及转换式两件式蘑菇形穿透性角膜移植术治疗疱疹性角膜瘢痕的疗效
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4
Large-Diameter Modified Big-Bubble Deep Anterior Lamellar Keratoplasty in Post-Radial Keratotomy Eyes.大直径改良深层板层角膜切开术治疗放射状角膜切开术后眼。
Am J Ophthalmol. 2023 Jul;251:1-4. doi: 10.1016/j.ajo.2022.12.012. Epub 2022 Dec 18.
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Deep anterior lamellar keratoplasty for keratoconus: Elements for success.圆锥角膜的深前板层角膜移植术:成功要素
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