Bischel Oliver E, Seeger Jörn B, Böhm Paul M
BG Trauma Center, University of Heidelberg, Ludwig-Guttmann-Str. 13, 67071 Ludwigshafen, Germany.
Parc Clinic, Am Kaiserberg 2-4, 61231 Bad Nauheim, Germany.
J Clin Med. 2025 Apr 1;14(7):2409. doi: 10.3390/jcm14072409.
: The use of tapered monobloc stems in revision total hip arthroplasty (RTHA) has shown excellent results, with low implant-dependent failures due to aseptic loosening. Infection is one of the main failure reasons, but further problems, like periprosthetic fractures (PPFs), may endanger the function and duration of the implant in the long run. : A consecutive series of 121 cases after femoral RTHA with a monobloc device was retrospectively investigated, and a Kaplan-Meier analysis was performed. The mean follow-up was 13.0 (range: 0.8-23.8) years. : PPF occurred in six patients during follow-up. The cumulative risk for PPF was 5.2% (95% CI: 1.1-9.4%) after 23.8 years. Female gender was associated with a significantly higher risk compared to male gender (9.1% (95% CI: 2.1-16.1%) after 23.1 years vs. 0% after 23.8 years; log-rank = 0.0034). Patients operated with stems with a length equal to or longer than the calculated median length were also at a significantly higher risk of PPF during follow-up (10.2% (95% CI: 2.4-17.9%) after 23.8 years vs. 0% after 23.1 years; log-rank = 0.0158). Diabetes at the time of index operation also significantly influenced the occurrence of a PPF during follow-up (n = 4 patients with PPF out of 107 without (4.0% (95% CI: 0.2-7.8%) after 23.8 years vs. n = 2 out of 14 with diabetes (15.4% (95% CI: 0-35.0%) after 21.1 years; log-rank = 0.0368). The failure rate with implant removal as an endpoint due to aseptic loosening was 0%, and with infection it was 3.4% (95% CI: 0.1-6.7%), after 23.8 years. : Although no removal of the implant due to a PPF was necessary, the cumulative risk for PPF after femoral revision with a tapered and fluted monobloc stem was higher in this long-term follow-up series compared to implant failure due to infection or aseptic loosening. Female gender and diabetes was associated with a significantly higher risk of PPF during follow-up. The use of longer stems than necessary is not preventive of PPF, and should be avoided.
在翻修全髋关节置换术(RTHA)中使用锥形一体式股骨柄已显示出优异的效果,因无菌性松动导致的植入物相关失败率较低。感染是主要的失败原因之一,但其他问题,如假体周围骨折(PPF),从长远来看可能会危及植入物的功能和使用寿命。
对连续121例采用一体式装置进行股骨RTHA术后的病例进行回顾性研究,并进行Kaplan-Meier分析。平均随访时间为13.0年(范围:0.8 - 23.8年)。
随访期间有6例患者发生PPF。23.8年后PPF的累积风险为5.2%(95%可信区间:1.1 - 9.4%)。与男性相比,女性发生PPF的风险显著更高(23.1年后为9.1%(95%可信区间:2.1 - 16.1%),23.8年后为0%;对数秩检验P = 0.0034)。使用长度等于或长于计算出的中位数长度的股骨柄进行手术的患者在随访期间发生PPF的风险也显著更高(23.8年后为10.2%(95%可信区间:2.4 - 17.9%),23.1年后为0%;对数秩检验P = 0.0158)。初次手术时患有糖尿病也显著影响随访期间PPF的发生(107例无糖尿病患者中有4例发生PPF(23.8年后为4.0%(95%可信区间:0.2 - 7.8%)),14例糖尿病患者中有2例发生PPF(21.1年后为15.4%(95%可信区间:0 - 35.0%);对数秩检验P = 0.0368)。以无菌性松动为终点的植入物取出失败率为0%,以感染为终点的失败率在23.8年后为3.4%(95%可信区间:0.1 - 6.7%)。
尽管无需因PPF而取出植入物,但在这个长期随访系列中,与因感染或无菌性松动导致的植入物失败相比,采用锥形带槽一体式股骨柄进行股骨翻修术后PPF的累积风险更高。女性和糖尿病患者在随访期间发生PPF的风险显著更高。使用不必要的长柄并不能预防PPF,应避免使用。