Cheng Shuai, Lv Wenhao, You Tingjing, Zhang Shengmin
The First Affiliated Hospital of Ningbo University, Ningbo, China.
Ningbo University, Ningbo, China.
Abdom Radiol (NY). 2025 Apr 12. doi: 10.1007/s00261-025-04909-9.
To investigate whether there is any effect of preprandial and postprandial states of patients on Ultrasound-derived fat fraction(UDFF) in liver fat content measurement.
A retrospective study was conducted on 1596 patients who underwent UDFF from January to September 2024; UDFF measurements were performed by a sonographer, who repeated each measurement 5 times before and after meals, respectively, and finally expressed them as the mean; then paired t-tests and analyses of variance (ANOVA) were used to compare the differences in preprandial and postprandial UDFF and Auto p-SWE( Auto point shear wave elastography) values among groups, and linear regression was used to analyze the differences in preprandial and postprandial UDFF and Auto p-SWE values between each group.
The study enrolled 1036 patients(491 males and 545 females), aged 18-89 years, mean age (56.50 ± 14.67) years. The differences in UDFF and Auto p-SWE values between the group eating protein and fatty foods (n = 613) and the group eating light foods (n = 423) were not statistically significant (p > 0.05); the differences in UDFF and Auto p-SWE values between the group with a body mass index(BMI) < 25 kg/m2 (n = 703) and the group with a BMI ≥ 25 kg/m2 (n = 333) were statistically significant (p < 0.05). Preprandial and postprandiall UDFF and Auto p-SWE values were highly positively correlated in the eating group, the protein and greasy food group, and the light food group (r = 0.985, 0.983, 0.988, r = 0.834, 0.849, 0.810, all p < 0.001).
UDFF has good consistency in the measurement of liver fat content in preprandial and postprandial states.
探讨患者的餐前和餐后状态对肝脏脂肪含量测量中超声衍生脂肪分数（UDFF）是否有影响。
对2024年1月至9月接受UDFF检查的1596例患者进行回顾性研究；UDFF测量由一名超声检查人员进行，其分别在饭前和饭后重复测量5次，最后将结果表示为平均值；然后采用配对t检验和方差分析（ANOVA）比较各组餐前和餐后UDFF及自动点剪切波弹性成像（Auto p-SWE）值的差异，并采用线性回归分析各组之间餐前和餐后UDFF及Auto p-SWE值的差异。
该研究纳入了1036例患者（男性491例，女性545例），年龄18 - 89岁，平均年龄（56.50±14.67）岁。食用蛋白质和脂肪类食物组（n = 613）与食用清淡食物组（n = 423）之间的UDFF和Auto p-SWE值差异无统计学意义（p > 0.05）；体重指数（BMI）< 25 kg/m²组（n = 703）与BMI≥25 kg/m²组（n = 333）之间的UDFF和Auto p-SWE值差异有统计学意义（p < 0.05）。在进食组、蛋白质和油腻食物组以及清淡食物组中，餐前和餐后的UDFF及Auto p-SWE值呈高度正相关（r = 0.985、0.983、0.988，r = 0.834、0.849、0.810，均p < 0.001）。
UDFF在餐前和餐后状态下肝脏脂肪含量测量中具有良好的一致性。
