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IdeZ protease does not prevent convertase stabilization by C3 nephritic factors in C3 glomerulopathy.

作者信息

Stevens Kes H, Baas Laura M, van de Kar Nicole C A J, van den Heuvel Lambertus P W J, Michels Marloes A H M

机构信息

Department of Pediatric Nephrology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.

Department of Genetics, Translational Metabolic Laboratory, Radboud University Medical Center, Nijmegen, The Netherlands.

出版信息

Nephrol Dial Transplant. 2025 Aug 1;40(8):1628-1631. doi: 10.1093/ndt/gfaf065.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbb/12315799/773bd27136a1/gfaf065fig1.jpg

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本文引用的文献

1
Complement inhibitors for kidney disease.
Nephrol Dial Transplant. 2023 Nov 8;38(Supplement_2):ii29-ii39. doi: 10.1093/ndt/gfad079.
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Front Immunol. 2022 Nov 14;13:1036136. doi: 10.3389/fimmu.2022.1036136. eCollection 2022.
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Endopeptidase Cleavage of Anti-Glomerular Basement Membrane Antibodies in Severe Kidney Disease: An Open-Label Phase 2a Study.
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Imlifidase for the treatment of anti-HLA antibody-mediated processes in kidney transplantation.
Am J Transplant. 2022 Mar;22(3):691-697. doi: 10.1111/ajt.16828. Epub 2021 Sep 13.
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Unraveling the Molecular Mechanisms Underlying Complement Dysregulation by Nephritic Factors in C3G and IC-MPGN.
Front Immunol. 2018 Oct 15;9:2329. doi: 10.3389/fimmu.2018.02329. eCollection 2018.
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Rituximab for Treatment of Membranoproliferative Glomerulonephritis and C3 Glomerulopathies.
Biomed Res Int. 2017;2017:2180508. doi: 10.1155/2017/2180508. Epub 2017 May 9.
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Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation.
Kidney Int. 2012 Nov;82(10):1084-92. doi: 10.1038/ki.2012.250. Epub 2012 Aug 1.
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IdeS: a bacterial proteolytic enzyme with therapeutic potential.
PLoS One. 2008 Feb 27;3(2):e1692. doi: 10.1371/journal.pone.0001692.

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