Loerbroks Adrian, Yang Haiou, Bosch Jos A, Salandi Julia, Keymel Stefanie, Li Jian
Institute of Occupational, Social and Environmental Medicine, Centre for Health and Society, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Germany.
Center for Occupational and Environmental Health, University of California, Irvine, California, USA.
Am J Ind Med. 2025 Jun;68(6):508-515. doi: 10.1002/ajim.23722. Epub 2025 Apr 13.
Prior work has linked work stressors to asthma. However, research related to gender-specific associations remains sparse and yielded mixed results. We aimed to address this gap.
We drew on cross-sectional data from the 2015 National Health Interview Survey (individual-level response rate = 79.7%). Included were participants in employment who were aged 18-70 (n = 18,701). Work-to-family conflict, workplace bullying, and job insecurity were assessed as work stressors. Asthma was defined based on self-reports of a lifetime diagnosis by a doctor or other health professional. To account for the complex sampling design, variance estimation was used to compute weighted descriptive statistics and odds ratios (ORs) as well as corresponding 95% confidence intervals (CIs) using multivariable logistic regression. To test for interaction, interaction terms for work stressors and gender were included in additional models.
In the full sample, work-to-family conflict, workplace bullying and job insecurity showed positive associations with asthma (OR = 1.20, 95%CI = 1.03-1.40; OR = 1.45, 95%CI = 1.17-1.80; and OR = 1.20, 95%CI = 0.99-1.45, respectively). We did not observe meaningful gender differences in the magnitudes of the ORs. All interaction terms were not statistically significant.
Work stressors were positively associated with asthma, but there was no evidence of gender differences. Prospective studies are needed to determine the potential temporal relation of these associations.
先前的研究已将工作压力源与哮喘联系起来。然而,与性别特异性关联相关的研究仍然较少,且结果不一。我们旨在填补这一空白。
我们利用了2015年全国健康访谈调查的横断面数据(个体层面的回复率 = 79.7%)。纳入的是年龄在18 - 70岁的就业参与者(n = 18,701)。工作与家庭冲突、职场霸凌和工作不安全感被评估为工作压力源。哮喘是根据医生或其他健康专业人员对终生诊断的自我报告来定义的。为了考虑复杂的抽样设计,使用方差估计来计算加权描述性统计量和比值比(OR)以及使用多变量逻辑回归的相应95%置信区间(CI)。为了检验交互作用,在额外的模型中纳入了工作压力源和性别的交互项。
在整个样本中,工作与家庭冲突、职场霸凌和工作不安全感与哮喘呈正相关(OR分别为 = 1.20,95%CI = 1.03 - 1.40;OR = 1.45,95%CI = 1.17 - 1.80;OR = 1.20,95%CI = 0.99 - 1.45)。我们没有观察到OR大小方面有意义的性别差异。所有交互项均无统计学意义。
工作压力源与哮喘呈正相关,但没有证据表明存在性别差异。需要进行前瞻性研究来确定这些关联的潜在时间关系。