Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Ziemssenstr.1, 80336, Munich, Germany.
Institute for Medical Informatics, Biometry, and Epidemiology, LMU Munich, Munich, Germany.
Int Arch Occup Environ Health. 2019 Jul;92(5):673-681. doi: 10.1007/s00420-019-01402-x. Epub 2019 Jan 18.
This study analyzes the association of work-related stress with incident asthma and rhinitis in young adults with a special focus on gender-specific differences.
Incident asthma, wheezing and rhinitis were measured in a cohort of 2051 young German adults (aged 16-18 years at baseline) recruited by the prospective population-based SOLAR study (Study of Occupational Allergy Risks). Work-related stress was measured by the Trier Inventory for the Assessment of Chronic Stress (TICS). Two TICS scales, work overload and work discontent, were analysed. Logistic regression was conducted to calculate odds ratios (OR) and 95% confidence intervals (CI).
In females, the odds for incident asthma were found to be 17% higher for each increase of the work discontent score by one point (OR 1.17, 95% CI 1.04-1.31). In males, no association was statistically significant. Incident rhinitis showed no association with any exposure variable.
This study shows a link between work-related stress and incident asthma which seems to be confined to women. This study adds evidence about the association of work-related stress and asthma in young adults and can contribute to prevention for that particular age group.
本研究分析了工作相关压力与青年成年人哮喘和鼻炎发病的关联，特别关注了性别差异。
通过前瞻性人群基础 SOLAR 研究（职业过敏风险研究），对 2051 名年轻德国成年人（基线时年龄为 16-18 岁）进行了哮喘、喘息和鼻炎的发病测量。工作相关压力通过特里尔慢性应激评估量表（TICS）进行测量。分析了工作负荷过重和工作不满两个 TICS 量表。采用逻辑回归计算比值比（OR）和 95%置信区间（CI）。
在女性中，工作不满评分每增加一分，哮喘发病的几率增加 17%（OR 1.17，95% CI 1.04-1.31）。在男性中，无统计学意义。鼻炎发病与任何暴露变量均无关联。
本研究表明工作相关压力与哮喘发病之间存在关联，这种关联似乎仅限于女性。本研究为青年成年人工作相关压力与哮喘之间的关联提供了证据，并可为该特定年龄组的预防提供依据。
