Anghileri L J, Crône M C, Robert J
Neoplasma. 1985;32(3):369-73.
The experimental data suggest that permeability changes at the plasma membrane level are the most likely cause of the enhancement of tumor cell killing by hyperthermia in the presence of 1 mM La3+. The interaction of La3+ with the Na+, K+ ATPase and Ca2+-pump ATPase may be the probable cause of dramatic electrolyte changes which enhance the hyperthermia effects on tumor cells.
实验数据表明，在存在1 mM La3+的情况下，质膜水平的通透性变化最有可能是热疗增强肿瘤细胞杀伤作用的原因。La3+与Na+、K+ -ATP酶以及Ca2+ -泵ATP酶的相互作用可能是导致显著电解质变化的原因，而这种变化增强了热疗对肿瘤细胞的作用。
