Gao Lu-Ying, Ji Jiang, Xia Yu, Hu Ya, Ma Liyuan, Pan Aonan, An Yuang, Luo Nengwen, Jiang Yuxin
Department of Ultrasound, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Asia Pac J Clin Oncol. 2025 Aug;21(4):439-444. doi: 10.1111/ajco.14170. Epub 2025 Apr 13.
To analyze the ultrasound features of pancreatic cystic lesions and to compare contrast-enhanced sonography (CEUS) with magnetic resonance imaging (MRI) to investigate the diagnostic value of CEUS for pancreatic cystic lesions.
Patients with pancreatic cystic lesions who underwent CEUS examination and enhanced MRI from February 2022 to January 2023 at Peking Union Medical College Hospital were prospectively included. The diagnostic value of CEUS in the diagnosis of pancreatic cystic lesions was analyzed using postoperative histopathology as the gold standard and compared with enhanced MRI.
In total, 17 patients with pancreatic cystic lesions were included, the CEUS diagnostic accuracy was 76.47% (13/17), the enhanced MRI diagnostic accuracy was 64.71% (11/17), and the diagnostic results of CEUS were in moderate agreement with those of enhanced MRI (κ = 0.52). The CEUS features of all lesions were categorized into four types: Type I, unilocular cystic type, five cases; Type II, microcystic lesion type, four cases; Type III, macrocystic lesion type, two cases; and Type IV, lesion with an enhanced solid component, six cases. There were two cases of Type I and one case of Type II simple cysts. Pancreatic pseudocysts were Type I in one case. Of the pancreatic serous cystadenomas, three cases were Type II, two cases were Type III, and one case was Type IV. The case of pancreatic mucinous cystadenoma was Type I. For the intraductal papillary mucinous neoplasm, four cases were all Type IV. For solid pseudopapillary tumors of the pancreas, one case was classified as Type IV. One case of pancreatic neuroendocrine tumor was classified as Type I.
CEUS, as an economical, radiation-free, and effective imaging modality, can be an optional test for pancreatic cystic diseases and helps in their diagnosis and follow-up.
分析胰腺囊性病变的超声特征，并对比超声造影（CEUS）与磁共振成像（MRI），以探讨CEUS对胰腺囊性病变的诊断价值。
前瞻性纳入2022年2月至2023年1月在北京协和医院接受CEUS检查及增强MRI检查的胰腺囊性病变患者。以术后组织病理学为金标准，分析CEUS对胰腺囊性病变的诊断价值，并与增强MRI进行比较。
共纳入17例胰腺囊性病变患者，CEUS诊断准确率为76.47%（13/17），增强MRI诊断准确率为64.71%（11/17），CEUS与增强MRI的诊断结果具有中度一致性（κ = 0.52）。所有病变的CEUS特征分为四种类型：I型，单房囊性型，5例；II型，微囊性病变型，4例；III型，大囊性病变型，2例；IV型，有强化实性成分的病变，6例。I型和II型单纯囊肿各2例。胰腺假性囊肿1例为I型。胰腺浆液性囊腺瘤中，3例为II型，2例为III型，1例为IV型。胰腺黏液性囊腺瘤1例为I型。导管内乳头状黏液性肿瘤4例均为IV型。胰腺实性假乳头状肿瘤1例分类为IV型。胰腺神经内分泌肿瘤1例分类为I型。
CEUS作为一种经济、无辐射且有效的成像方式，可作为胰腺囊性疾病的一种可选检查方法，有助于其诊断和随访。
