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埃塞俄比亚东部公立医院分娩妇女的不良孕产妇结局:一项横断面研究。

Adverse maternal outcomes among women who gave birth at public hospitals in eastern Ethiopia: a cross-sectional study.

作者信息

Leta Masresha, Tura Abera Kenay, Mezmur Haymanot, Shiferaw Kasiye, Assefa Nega

机构信息

Department of Midwifery, Harar Health Science College, Harar, Ethiopia.

School of Nursing, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.

出版信息

Front Glob Womens Health. 2025 Mar 28;6:1569815. doi: 10.3389/fgwh.2025.1569815. eCollection 2025.

Abstract

BACKGROUND

An adverse maternal outcome, such as anemia, postpartum hemorrhage, and postpartum eclampsia, poses a significant risk to women. While studies on the burden of adverse maternal outcomes have been conducted in various countries, including Ethiopia, many predictors beyond obstetric factors have not been fully explored. This study aimed to determine the magnitude and factors associated with adverse maternal outcomes among women who gave birth at selected public hospitals in eastern Ethiopia.

METHODS

A hospital-based cross-sectional study was conducted among 2,608 randomly selected women who gave birth in six public hospitals in eastern Ethiopia from November 2023 to March 2024. Data were collected through face-to-face interviews and clinical chart reviews. Factors associated with adverse maternal outcomes were identified using bivariable and multivariable robust Poisson regression analyses. Adjusted relative risk (ARR) with a 95% confidence interval (CI) was used to report the strength of the association. The variables with a -value of <0.05 were considered statistically significant.

RESULTS

The magnitude of adverse maternal outcomes was 15.68% (95% CI: 14.70%-16.66%). A poor wealth index (ARR = 4.41; 95% CI: 3.46-5.62), having danger signs at admission (ARR = 1.86; 95% CI: 1.18-2.91), alcohol use during pregnancy (ARR = 1.86; 95% CI: 1.32-2.62), duration of labor ≥24 h (ARR = 1.69; 95% CI: 1.00-2.85), and maternal age greater than 35 years (ARR = 1.39; 95% CI: 1.03-1.86) increased the risk of adverse maternal outcomes. In contrast, folic acid intake during pregnancy (ARR = 0.47; 95% CI: 0.38-0.57), having partner support (ARR = 0.70; 95% CI: 0.59-0.83), and spontaneous vaginal delivery (ARR = 0.58; 95% CI: 0.49-0.68) reduced the risk of adverse maternal outcomes.

CONCLUSION

One in six women who gave birth in eastern Ethiopia experienced adverse maternal outcomes. This rate was determined to be moderate when compared to the WHO projections for lower- and middle-income countries and better than the higher averages reported by the WHO. Targeted intervention programs, such as targeted education and empowerment programs, and the strengthening of the community health worker program would help address socioeconomic disparities and improve early detection and management of danger signs during pregnancy, which would aid in averting the occurrence of adverse outcomes.

摘要

背景

贫血、产后出血和产后子痫等不良孕产妇结局对女性构成重大风险。虽然包括埃塞俄比亚在内的各个国家都开展了关于不良孕产妇结局负担的研究,但许多超出产科因素的预测因素尚未得到充分探索。本研究旨在确定埃塞俄比亚东部选定公立医院分娩的妇女中不良孕产妇结局的严重程度及相关因素。

方法

对2023年11月至2024年3月在埃塞俄比亚东部六家公立医院随机选取的2608名分娩妇女进行了一项基于医院的横断面研究。通过面对面访谈和临床病历审查收集数据。使用双变量和多变量稳健泊松回归分析确定与不良孕产妇结局相关的因素。采用调整相对风险(ARR)及95%置信区间(CI)报告关联强度。P值<0.05的变量被认为具有统计学意义。

结果

不良孕产妇结局的严重程度为15.68%(95%CI:14.70%-16.66%)。财富指数低(ARR = 4.41;95%CI:3.46-5.62)、入院时有危险体征(ARR = 1.86;95%CI:1.18-2.91)、孕期饮酒(ARR = 1.86;95%CI:1.32-2.62)、产程≥24小时(ARR = 1.69;95%CI:1.00-2.85)以及产妇年龄大于35岁(ARR = 1.39;95%CI:1.03-1.86)会增加不良孕产妇结局的风险。相比之下,孕期摄入叶酸(ARR = 0.47;95%CI:0.38-0.57)、有伴侣支持(ARR = 0.70;95%CI:0.59-0.83)以及自然阴道分娩(ARR = 0.58;95%CI:0.49-0.68)会降低不良孕产妇结局的风险。

结论

在埃塞俄比亚东部分娩的妇女中,六分之一经历了不良孕产妇结局。与世界卫生组织对低收入和中等收入国家的预测相比,这一比率被确定为中等,且优于世界卫生组织报告的较高平均值。有针对性的干预项目,如针对性教育和赋权项目以及加强社区卫生工作者项目,将有助于解决社会经济差距问题,并改善孕期危险体征的早期发现和管理,这将有助于避免不良结局的发生。

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