Vukovic Mirjana M Nedovic, Terzic Zoran S, Golubovic Mileta M, Bojic Milos D, Vukovic Marko M
Center for Health System Evidence and Research in Public Health, Institute of Public Health of Montenegro, Podgorica, Montenegro.
Faculty of Medicine, University of Montenegro, Podgorica, Montenegro.
Iran J Public Health. 2025 Feb;54(2):414-423.
Bladder cancer accounts for more than 200,000 deaths annually on a global level, with an age-standardized mortality rate of 2.9 per 100,000 individuals. Despite declining global rates, it remains a substantial public health burden. We aimed to analyze the mortality trend of bladder cancer in Montenegro and identify the measures taken to combat this tumor.
Bladder cancer mortality data in Montenegro from 1990 to 2021 were collected. Mortality rates were age-standardized to the World Standard Population. The joinpoint, linear and Poisson regressions were used to assess bladder cancer mortality trend.
There was a consistent increase in mortality rates due to bladder cancer, with statistical significance for both the overall population and specifically for males, with an average annual percent change (AAPC) of 1.5% (95% CI: 1.5 (0.5-2.9)) and 1.6% (AAPC (95% CI): 1.6 (0.4-3.3)) respectively. Additionally, there was a notable annual increase in the number of bladder cancer cases: average annual increase was 3.4% for the overall population, 3.5% in male and 2.9% in female, with statistical parameters (AAPC (95% CI), -value) for join point regression: 3.4 (2.4-4.8), <0.001; 3.5 (2.3-5.1), 0.003; and 2.9 (1.2-5.1), 0.004, respectively. The majority of bladder cancer deaths occurred in the age groups of 65-74 (35.8%), 75-84 (33.6%), and 55-64 (16.8%).
The ongoing increase in bladder cancer mortality in Montenegro, particularly among men and elderly should encourage policymakers to take action to reverse this unfavorable trend.
膀胱癌在全球范围内每年导致超过20万人死亡，年龄标准化死亡率为每10万人2.9例。尽管全球发病率呈下降趋势，但它仍然是一个重大的公共卫生负担。我们旨在分析黑山共和国膀胱癌的死亡率趋势，并确定为对抗这种肿瘤所采取的措施。
收集了黑山共和国1990年至2021年的膀胱癌死亡率数据。死亡率按照世界标准人口进行年龄标准化。采用连接点、线性和泊松回归分析膀胱癌死亡率趋势。
膀胱癌死亡率持续上升，总体人群及男性死亡率均具有统计学意义，平均年变化百分比（AAPC）分别为1.5%（95%CI：1.5（0.5 - 2.9））和1.6%（AAPC（95%CI）：1.6（0.4 - 3.3））。此外，膀胱癌病例数每年显著增加：总体人群平均年增长率为3.4%，男性为3.5%，女性为2.9%，连接点回归的统计参数（AAPC（95%CI），P值）分别为：3.4（2.4 - 4.8），<0.001；3.5（2.3 - 5.1），0.003；2.9（1.2 - 5.1），0.004。大多数膀胱癌死亡发生在65 - 74岁（35.8%）、75 - 84岁（33.6%）和55 - 64岁（16.8%）年龄组。
黑山共和国膀胱癌死亡率持续上升，尤其是在男性和老年人中，这应促使政策制定者采取行动扭转这一不利趋势。
