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从肥胖到炎症:前列腺癌与代谢综合征研究的新前沿

From obesity to inflammation: emerging frontiers in prostate cancer and metabolic syndrome studies.

作者信息

Xu Xi, Xu Jinshan, Gao Hongliang, Sheng Zhaoyang, Xu Yang, Zeng Shuxiong, Chen Guanghua, Zhang Zhensheng

机构信息

Department of Urology, First Affiliated Hospital, Naval Medical University, Shanghai, China.

Department of Support, Unit 31635 of Chinese People's Liberation Army, Guilin, China.

出版信息

Transl Androl Urol. 2025 Mar 30;14(3):553-566. doi: 10.21037/tau-2024-671. Epub 2025 Mar 26.

Abstract

BACKGROUND

According to recent studies, prostate cancer (PCa) is strongly associated with metabolic syndrome (MetS). However, there has not been any bibliometric visual analysis of relevant papers. In order to acquire knowledge about research settings and possible future paths, a thorough bibliometric study of MetS-related PCa research was carried out.

METHODS

From January 1, 2004 to December 31, 2023, original and review publications about MetS and PCa were retrieved from the Web of Science Core Collection (WOSCC) database. Analysis of co-authorship and co-occurrence was done using VOSviewer. To find the top terms with the greatest citation burst, CiteSpace was used.

RESULTS

There were 1,296 publications on PCa and MetS in all. The analysis showed that the number of yearly scientific papers in the sector was on the rise. The three most productive nations were China, Italy, and the USA. Most papers were published in the , while most citations were obtained by the . The most influential author in terms of citations was Professor Smith MR, whereas the most prolific author was Professor Freedland SJ. Keyword analysis revealed that, apart from PCa and MetS, "obesity" was the most often used phrase, with "risk", "meta-analysis", and "inflammation" appearing as study subjects. Furthermore, "components" and "sex hormones" gained more and more attention.

CONCLUSIONS

The findings provide a thorough understanding of the larger context of this field of study. Future studies need to investigate PCa's metabolic processes and inflammatory mechanism. Furthermore, switching from observational research to meta-analysis offers the possibility of illness prediction and tailored therapies. These results may help researchers navigate the most recent advancements and influence the field's future paths.

摘要

背景

根据最近的研究,前列腺癌(PCa)与代谢综合征(MetS)密切相关。然而,尚未对相关论文进行任何文献计量可视化分析。为了了解研究背景和可能的未来发展方向,对与MetS相关的PCa研究进行了全面的文献计量研究。

方法

从2004年1月1日至2023年12月31日,从Web of Science核心合集(WOSCC)数据库中检索关于MetS和PCa的原创性和综述性出版物。使用VOSviewer进行合著和共现分析。为了找出具有最大引文爆发的顶级术语,使用了CiteSpace。

结果

关于PCa和MetS的出版物共有1296篇。分析表明,该领域的年度科学论文数量呈上升趋势。三个产出最多的国家是中国、意大利和美国。大多数论文发表在 ,而大多数被引用的论文来自 。在被引次数方面最有影响力的作者是史密斯·MR教授,而产量最高的作者是弗里德兰·SJ教授。关键词分析显示,除了PCa和MetS外,“肥胖”是最常用的词汇,“风险”“荟萃分析”和“炎症”作为研究主题出现。此外,“成分”和“性激素”越来越受到关注。

结论

这些发现提供了对该研究领域更广泛背景的全面理解。未来的研究需要调查PCa的代谢过程和炎症机制。此外,从观察性研究转向荟萃分析为疾病预测和个性化治疗提供了可能性。这些结果可能有助于研究人员了解最新进展并影响该领域的未来发展方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/11986549/aaec4742741b/tau-14-03-553-f1.jpg

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