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人参多糖的知识图谱与全球研究趋势:1985年至2023年的文献计量可视化分析

Knowledge Mapping and Global Research Trends of Ginseng Polysaccharides: a Bibliometric Analysis with Visualizations from 1985 to 2023.

作者信息

Mo Pingli, Gao Bowen, Wang Rui, Huang Shiying, Chen Qiugu, Li Muxia, Wu Jiazhen, Zhang Shangbin, Chen Jianping

机构信息

Shenzhen Key Laboratory of Hospital Chinese Medicine Preparation, Shenzhen Traditional Chinese Medicine Hospital, the Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, People's Republic of China.

Department of Traditional Chinese Medicine, the Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, People's Republic of China.

出版信息

Drug Des Devel Ther. 2025 Apr 9;19:2749-2766. doi: 10.2147/DDDT.S508387. eCollection 2025.

Abstract

BACKGROUND

C. A. Meyer (Ginseng) has a lengthy historical background of utilization and is frequently utilized for the treatment and prevention of various diseases. In recent times, researchers have shown an increasing inclination towards investigating the extraction, purification, structural analysis, and pharmacological properties of polysaccharides present in ginseng. However, there was still a lack of comprehensive and integrated analysis of ginseng polysaccharides.

METHODS

This study employed the Web of Science Core Collection (WoSCC) as the data source and utilized software tools including Bibliometrix R Package, VOSviewer, and CiteSpace for the purpose of conducting data visualization and analysis of ginseng polysaccharides publications.

RESULTS

China emerged as the foremost and most impactful nation in the realm of ginseng polysaccharide research, fostering robust collaborative ties with Republic of Korea and the USA. Yifa Zhou was the most influential author and the International Journal of Biological Macromolecules exerted as the significant influence in this field. The reference DUBOIS M, 1956, ANAL CHEM, V28, P350 received the highest citations. Through a comprehensive examination results of keywords clustering, keywords with the strong burst, and trend topic, the research hot directions of ginseng polysaccharides were focused on structural analysis and pharmacological activities. Specifically, gut microbiota and oxidative stress were active research hotspots of investigating the pharmacological activities of ginseng polysaccharides at present, it also was corroborated in disciplinary category analysis.

CONCLUSION

This study revealed the multidimensional field of research on ginseng polysaccharides. Current hot research directions encompassed structural analysis and pharmacological activities in this field, with research hotspots focused on exploring the pharmacological activities of ginseng polysaccharides in gut microbiota and oxidative stress.

摘要

背景

人参具有悠久的应用历史,常用于治疗和预防各种疾病。近年来,研究人员越来越倾向于研究人参中多糖的提取、纯化、结构分析和药理特性。然而,对于人参多糖仍缺乏全面综合的分析。

方法

本研究以科学网核心合集(WoSCC)为数据源,利用Bibliometrix R包、VOSviewer和CiteSpace等软件工具,对人参多糖相关出版物进行数据可视化和分析。

结果

中国在人参多糖研究领域成为最重要且最具影响力的国家,与韩国和美国建立了紧密的合作关系。周义发是最具影响力的作者,《国际生物大分子杂志》在该领域发挥了重要影响。参考文献DUBOIS M, 1956, ANAL CHEM, V28, P350获得的引用次数最多。通过对关键词聚类、关键词突现和趋势主题的综合考察结果,人参多糖的研究热点方向集中在结构分析和药理活性方面。具体而言,肠道微生物群和氧化应激是目前研究人参多糖药理活性的活跃研究热点,这在学科类别分析中也得到了证实。

结论

本研究揭示了人参多糖研究的多维度领域。当前该领域的热门研究方向包括结构分析和药理活性,研究热点集中在探索人参多糖在肠道微生物群和氧化应激方面的药理活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc29/11994077/cff639238fc5/DDDT-19-2749-g0001.jpg

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