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免疫球蛋白G4相关疾病的喉部表现:一种难以捉摸的危及生命的病症。

Laryngeal Manifestation of Immunoglobulin G4-Related Disease: An Elusive Life-Threatening Entity.

作者信息

Negi Sakshi, Parsana Monil, Sharma Vikas, Panda Naresh Kumar, Gupta Kirti

机构信息

Department of Otolaryngology, Post Graduate Institute of Medical Education & Research, Chandigarh, 160012 India.

Dept of Histopathology, Post Graduate Institute of Medical Education & Research, Chandigarh, 160012 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2025 Apr;77(4):1950-1954. doi: 10.1007/s12070-025-05438-z. Epub 2025 Mar 27.

Abstract

Immunoglobulin G4-related disease is a chronic fibro-inflammatory condition characterized by raised serum IgG4 concentrations, which with tissue infiltration by IgG4 plasma cells leads to pseudotumor formation in various organs. Primary presentation is very rare and is life threatening. This is only the 16th reported case of Immunoglobulin G4-related disease with primary laryngeal involvement worldwide and is the first reported case in the Indian population.

摘要

免疫球蛋白G4相关性疾病是一种慢性纤维炎症性疾病,其特征为血清免疫球蛋白G4浓度升高,IgG4浆细胞浸润组织导致各器官出现假瘤形成。原发性表现非常罕见且危及生命。这是全球第16例报道的原发性喉部受累的免疫球蛋白G4相关性疾病病例,也是印度人群中的首例报道病例。

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本文引用的文献

3
IgG4-related disease with pseudotumor formation in the larynx.喉内 IgG4 相关疾病伴假瘤形成。
Auris Nasus Larynx. 2020 Apr;47(2):305-308. doi: 10.1016/j.anl.2019.05.008. Epub 2019 Jun 21.
9
Consensus statement on the pathology of IgG4-related disease.关于 IgG4 相关疾病病理学的共识声明。
Mod Pathol. 2012 Sep;25(9):1181-92. doi: 10.1038/modpathol.2012.72. Epub 2012 May 18.

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