Villa Roberto Edoardo, Azimonti Giovanna, Bonos Eleftherios, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Gehring Ronette, Glandorf Boet, Kouba Maryline, López-Alonso Marta, Marcon Francesca, Nebbia Carlo, Pechová Alena, Prieto-Maradona Miguel, Röhe Ilen, Theodoridou Katerina, Galobart Jaume, Vettori Maria Vittoria, Navarro-Villa Alberto
EFSA J. 2025 Apr 11;23(4):e9350. doi: 10.2903/j.efsa.2025.9350. eCollection 2025 Apr.
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the efficacy of guanidinoacetic acid (GAA; Creamino®), intended for use as zootechnical additive (functional group: other zootechnicals - improvement of performance parameters) for weaned piglets and pigs for fattening in water for drinking. The additive is already authorised for use in feed and water for chickens for fattening and chickens reared for laying/breeding and only for feed in weaned piglets and pigs for fattening. In the previous opinion, the Panel concluded that the additive is safe for chickens for fattening, chickens reared for laying/breeding, piglets and pigs for fattening, the consumer, users and the environment under the proposed conditions of use. In the current submission, the applicant submitted considerations to support the authorisation of GAA in water for drinking for weaned piglets and pigs for fattening. The FEEDAP Panel reiterates it previous conclusion that the use of GAA in feed and water for drinking of weaned piglets and pigs for fattening has the potential to be efficacious in improving the zootechnical performance of the target animals under the proposed conditions of use (600-1200 mg GAA/kg complete feed; 200-600 mg GAA/L water).
应欧盟委员会的要求，动物饲料添加剂及产品或物质专家小组（FEEDAP）被要求就胍基乙酸（GAA；Creamino®）的功效提供科学意见，该产品拟用作断奶仔猪和育肥猪的畜牧技术添加剂（功能类别：其他畜牧技术——改善生产性能参数），通过饮水给药。该添加剂已被批准用于育肥鸡和产蛋/种用鸡的饲料和饮水中，而在断奶仔猪和育肥猪中仅批准用于饲料。在之前的意见中，专家小组得出结论，在所提议的使用条件下，该添加剂对育肥鸡、产蛋/种用鸡、仔猪和育肥猪、消费者、使用者及环境均安全。在本次提交的材料中，申请人提交了相关考量因素，以支持批准GAA用于断奶仔猪和育肥猪的饮水。FEEDAP专家小组重申其先前的结论，即在断奶仔猪和育肥猪的饲料和饮水中使用GAA，在所提议的使用条件下（每千克全价饲料含600 - 1200毫克GAA；每升水含200 - 600毫克GAA），有提高目标动物畜牧技术性能的潜力。
