Villa Roberto Edoardo, Azimonti Giovanna, Bonos Eleftherios, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Gehring Ronette, Glandorf Boet, Kouba Maryline, López-Alonso Marta, Marcon Francesca, Nebbia Carlo, Pechová Alena, Prieto-Maradona Miguel, Röhe Ilen, Theodoridou Katerina, Galobart Jaume, Casanova Jordi Ortuño, Vettori Maria Vittoria, Tarrés-Call Jordi, Navarro-Villa Alberto
EFSA J. 2025 Apr 11;23(4):e9349. doi: 10.2903/j.efsa.2025.9349. eCollection 2025 Apr.
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of guanidinoacetic acid (GAA) when used as zootechnical additive in feed and water for drinking for turkeys for fattening and turkeys reared for breeding, and a preparation of GAA when used in feed for the same target species. The FEEDAP Panel concluded that GAA at 1200 mg/kg complete feed or 600 mg/L water is safe for turkeys for fattening and turkeys reared for breeding. There is no concern on consumer safety resulting from the use of GAA for turkeys at the proposed conditions of use. GAA is not toxic by inhalation, not irritant to skin and eyes and not a dermal sensitiser. The FEEDAP Panel concluded that the use of GAA as feed additive is not expected to pose a risk to the environment. The use of the additive under assessment in animal nutrition at the proposed conditions of use has the potential to be efficacious in turkeys for fattening and turkeys reared for breeding. The above conclusions apply to both the active substance GAA and the preparation of GAA.
应欧盟委员会的要求，动物饲料中使用的添加剂及产品或物质专家小组（FEEDAP）被要求就胍基乙酸（GAA）用作育肥火鸡和种用火鸡饲料及饮用水中的畜牧学添加剂时的安全性和有效性，以及GAA制剂用于相同目标物种的饲料时的安全性和有效性发表科学意见。FEEDAP专家小组得出结论，在全价饲料中添加1200 mg/kg或在饮水中添加600 mg/L的GAA对育肥火鸡和种用火鸡是安全的。在建议的使用条件下，火鸡使用GAA不会对消费者安全造成担忧。GAA吸入无毒，对皮肤和眼睛无刺激性，也不是皮肤致敏剂。FEEDAP专家小组得出结论，使用GAA作为饲料添加剂预计不会对环境构成风险。在所建议的使用条件下，评估中的添加剂用于动物营养有提高育肥火鸡和种用火鸡生产性能的潜力。上述结论适用于活性物质GAA和GAA制剂。
