Aygun Emre, Aygun Sibel Tugce, Turkmenoglu Yelda, Irdem Ahmet, Dursun Hasan
Department of Pediatrics, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Türkiye.
Sisli Etfal Hastan Tıp Bul. 2025 Mar 18;59(1):89-97. doi: 10.14744/SEMB.2024.02679. eCollection 2025.
The primary aim of this study was to evaluate the effects of nocturnal enuresis (NE) on Health-Related Quality of Life (HRQoL) in children with a special emphasis on the domains of HRQoL.
This was a case-control study in which consecutive children with NE were recruited along with their parents. Age and sex-matched children without enuresis served as controls. Age-appropriate children and proxy versions of the German Quality of Life Questionnaire (KINDL) were used to evaluate HRQoL and its domains. The clinicodemographic characteristics and family data were collected. HRQoL and the domain scores were compared between the patients and the control subjects.
100 children (50 of whom are males) with enuresis along with their parents were included in the study. 100 children served as the control group. The mean age of the patients was 9.58±2.77 years, and was no different from that of the control group. 55% of the children were receiving treatment for NE. The most common treatment was the nighttime waking (40%). The most commonly used drug was desmopressin. The median score of the health-related quality of life was 78.8 [69.2-83.3] in children with NE versus 90 [86.7-91.7] in the control group (p<0.001). In all domains, the median scores were significantly lower in children with NE compared with the controls.
Turkish children with NE had a significantly lower HRQoL score compared with children without NE. All the domain scores were also significantly lower in children with NE compared with the control subjects.
本研究的主要目的是评估夜间遗尿（NE）对儿童健康相关生活质量（HRQoL）的影响，特别关注HRQoL的各个领域。
这是一项病例对照研究，连续招募患有NE的儿童及其父母。年龄和性别匹配的无遗尿儿童作为对照。使用适合年龄的儿童和德国生活质量问卷（KINDL）的代理版本来评估HRQoL及其领域。收集临床人口统计学特征和家庭数据。比较患者和对照受试者的HRQoL及领域得分。
100名患有遗尿症的儿童（其中50名男性）及其父母被纳入研究。100名儿童作为对照组。患者的平均年龄为9.58±2.77岁，与对照组无差异。55%的儿童正在接受NE治疗。最常见的治疗方法是夜间唤醒（40%）。最常用的药物是去氨加压素。NE儿童的健康相关生活质量中位数得分为78.8 [69.2 - 83.3]，而对照组为90 [86.7 - 91.7]（p<0.001）。在所有领域，NE儿童的中位数得分均显著低于对照组。
与无NE的儿童相比，土耳其患有NE的儿童HRQoL得分显著更低。与对照受试者相比，NE儿童的所有领域得分也显著更低。
