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采用血流导向治疗一名10岁儿童巨大颈内动脉终末段动脉瘤:长期疗效及经验教训

Treatment of a giant terminal internal carotid artery aneurysm in a 10-year-old child by flow diversion: long-term outcome and lessons learned.

作者信息

Kuker Wilhelm, Jayamohan Jayaratnam

机构信息

Department of Clinical Neuroscience, University of Oxford, Oxford OX3 9DU, United Kingdom.

出版信息

BJR Case Rep. 2025 Mar 28;11(2):uaaf024. doi: 10.1093/bjrcr/uaaf024. eCollection 2025 Mar.

Abstract

A 28-mm diameter and partially thrombosed intracranial aneurysm was found in a 10-year-old boy on an MRI for non-specific headaches. The large neck incorporated the left internal carotid artery (ICA) termination and proximal middle cerebral artery. Treatment was planned to prevent further growth and rupture. Because of the difficult anatomy, a braided stent was first placed across the aneurysm neck as a scaffold to allow for the placement of a flow-diverting stent after its endothelialisation. However, severe stent-induced endothelial hyperplasia was encountered when the flow diverter was inserted. This resulted in a transient ICA occlusion during the procedure before flow was restored by angioplasty. As a result, the patient suffered a mild transient dysphasia but permanent loss of vision in the left eye. All antiplatelet medications were stopped 1 year after the procedure without problem. The aneurysm has remained fully occluded in the 7 years since.

摘要

一名10岁男孩因非特异性头痛行MRI检查时,发现一个直径28毫米、部分血栓形成的颅内动脉瘤。动脉瘤大颈包含左颈内动脉(ICA)末端和大脑中动脉近端。计划进行治疗以防止其进一步生长和破裂。由于解剖结构复杂,首先放置一个编织支架横跨动脉瘤颈部作为支架,以便在其内皮化后放置血流导向支架。然而,插入血流导向装置时遇到严重的支架诱导性内皮增生。这导致术中ICA短暂闭塞,随后通过血管成形术恢复血流。结果,患者出现轻度短暂性失语,但左眼永久性失明。术后1年停用所有抗血小板药物,未出现问题。此后7年,动脉瘤一直完全闭塞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e81b/11992335/ea1117d619b0/uaaf024f1.jpg

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