[New systemic treatment approaches for malignant eyelid tumors].

Malignant tumors of the eyelids represent a diagnostic and therapeutic challenge. Modern treatment approaches, such as targeted treatment and immunotherapy are becoming increasingly more important, particularly in advanced and metastatic stages; however, these can cause side effects such as fatigue, skin reactions and gastrointestinal complaints, which require close monitoring. An effective treatment option for advanced, metastasized or inoperable basal cell carcinoma is the well-manageable oral treatment with hedgehog inhibitors; however, these innovative, systemic treatment approaches require an individually adapted management, which is determined by an interdisciplinary tumor board and accompanied by a specialized, multiprofessional team to ensure optimal patient care.