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软组织肉瘤的新型分子方法：从诊断到治疗诊断学

Novel Molecular Methods in Soft Tissue Sarcomas: From Diagnostics to Theragnostics.

作者信息

Frazzette Nicholas, Jour George

机构信息

Department of Pathology, NYU Grossman School of Medicine, New York, NY 10016, USA.

出版信息

Cancers (Basel). 2025 Apr 3;17(7):1215. doi: 10.3390/cancers17071215.

DOI:10.3390/cancers17071215
PMID:40227789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11987812/
Abstract

Soft tissue sarcomas (STSs) are a diverse group of malignant tumors derived from mesenchymal tissues [...].

摘要

软组织肉瘤（STSs）是一组源自间充质组织的多种恶性肿瘤[...]。

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Cancer Gene Ther. 2025 Jan;32(1):11-21. doi: 10.1038/s41417-024-00856-7. Epub 2024 Nov 24.
2
Investigating the Use of Circulating Tumor DNA for Sarcoma Management.探索循环肿瘤DNA在肉瘤治疗中的应用。
J Clin Med. 2024 Oct 31;13(21):6539. doi: 10.3390/jcm13216539.
3
Introduction and impact of routine whole genome sequencing in the diagnosis and management of sarcoma.肉瘤诊断和管理中常规全基因组测序的介绍和影响。
Br J Cancer. 2024 Sep;131(5):860-869. doi: 10.1038/s41416-024-02721-8. Epub 2024 Jul 12.
4
Advances in spatial transcriptomics and its applications in cancer research.空间转录组学的进展及其在癌症研究中的应用。
Mol Cancer. 2024 Jun 20;23(1):129. doi: 10.1186/s12943-024-02040-9.
5
Recommendations for Tumor Mutational Burden Assay Validation and Reporting: A Joint Consensus Recommendation of the Association for Molecular Pathology, College of American Pathologists, and Society for Immunotherapy of Cancer.肿瘤突变负荷检测验证与报告的建议：分子病理学会、美国病理学家学院和癌症免疫治疗学会的联合共识建议。
J Mol Diagn. 2024 Aug;26(8):653-668. doi: 10.1016/j.jmoldx.2024.05.002. Epub 2024 Jun 6.
6
Comprehensive Genomic Profiling Alters Clinical Diagnoses in a Significant Fraction of Tumors Suspicious of Sarcoma.全面基因组分析改变了疑似肉瘤肿瘤中相当一部分的临床诊断。
Clin Cancer Res. 2024 Jun 14;30(12):2647-2658. doi: 10.1158/1078-0432.CCR-24-0384.
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Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal stromal tumors at single-cell resolution.解析单细胞分辨率下晚期胃肠间质瘤伊马替尼耐药的肿瘤免疫微环境。
Cell Death Dis. 2024 Mar 5;15(3):190. doi: 10.1038/s41419-024-06571-3.
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