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家兔窒息时的局部血管反应

Regional vascular responses to asphyxia in the rabbit.

作者信息

Wyler F, Hof R

出版信息

Eur J Clin Invest. 1977 Feb;7(1):67-70. doi: 10.1111/j.1365-2362.1977.tb01572.x.

DOI:10.1111/j.1365-2362.1977.tb01572.x
PMID:402279
Abstract

Organ blood flow was measured in eight spontaneously breathing male New Zealand white rabbits exposed to a 50 min period of asphyxia. The results were compared with eight control animals. Cardiac output and arterial pressure did not change. There was increased flow to the heart, brain and diaphragm. Flow to the kidneys and adipose tissue was reduced. Flow to the gastro-intestinal tract, liver, skeletal muscle and carcass was unchanged. Prolonged moderate asphyxia produces preferential blood supply to vital organs and maintains flow to the skeletal musculature and the gastro-intestinal tract; their blood supply is diverted mainly from the kidneys. These changes are similar to those seen in haemorrhagic and endotoxic shock in the rabbit.

摘要

在八只自主呼吸的雄性新西兰白兔身上测量了器官血流量,这些兔子经历了50分钟的窒息期。将结果与八只对照动物进行比较。心输出量和动脉压没有变化。心脏、大脑和膈肌的血流量增加。肾脏和脂肪组织的血流量减少。胃肠道、肝脏、骨骼肌和躯体的血流量没有变化。长时间的中度窒息会使重要器官获得优先供血,并维持骨骼肌和胃肠道的血流;它们的血液供应主要从肾脏转移。这些变化与兔子失血性休克和内毒素性休克中观察到的变化相似。

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