Reprogrammed Smooth Muscle Cells for Vascular Repair: A New Path to Healing Ischemic Tissue.
作者信息
Qian Li
机构信息
Department of Pathology and Laboratory Medicine, McAllister Heart Institute, School of Medicine, University of North Carolina at Chapel Hill.
出版信息
Circulation. 2025 Apr 15;151(15):1095-1097. doi: 10.1161/CIRCULATIONAHA.124.072958. Epub 2025 Apr 14.
Abstract
摘要
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本文引用的文献
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Novel Directly Reprogrammed Smooth Muscle Cells Promote Vascular Regeneration as Microvascular Mural Cells.新型直接重编程平滑肌细胞作为微血管壁细胞促进血管再生。
Circulation. 2025 Apr 15;151(15):1076-1094. doi: 10.1161/CIRCULATIONAHA.124.070217. Epub 2025 Feb 13.
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Direct conversion of cardiac fibroblasts into endothelial-like cells using Sox17 and Erg.利用 Sox17 和 Erg 将心脏成纤维细胞直接转化为内皮样细胞。
Nat Commun. 2024 May 16;15(1):4170. doi: 10.1038/s41467-024-48354-6.
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Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression.通过 ETS 因子和 TGFβ 抑制，高效地将成熟羊膜细胞直接重编程为内皮细胞。
Cell. 2012 Oct 26;151(3):559-75. doi: 10.1016/j.cell.2012.09.032. Epub 2012 Oct 18.
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A perivascular origin for mesenchymal stem cells in multiple human organs.多种人体器官中间充质干细胞的血管周围起源。
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Activation of cardiac and smooth muscle-specific genes in primary human cells after forced expression of human myocardin.在人心肌转录辅激活因子被迫表达后，原代人细胞中心脏和平滑肌特异性基因的激活。
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Forced expression of myocardin is not sufficient for induction of smooth muscle differentiation in multipotential embryonic cells.心肌素的强制表达不足以诱导多能胚胎细胞向平滑肌分化。
Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1596-601. doi: 10.1161/01.ATV.0000137190.63214.c5. Epub 2004 Jul 1.
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Myocardin is a master regulator of smooth muscle gene expression.心肌素是平滑肌基因表达的主要调节因子。
Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7129-34. doi: 10.1073/pnas.1232341100. Epub 2003 May 19.
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Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor.血清反应因子的转录辅因子心肌素对心脏基因表达的激活作用。
Cell. 2001 Jun 29;105(7):851-62. doi: 10.1016/s0092-8674(01)00404-4.
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