Lance P, Gibson-Glubb S, Gazzard J A, Gazzard B G
Postgrad Med J. 1985 May;61(715):411-3. doi: 10.1136/pgmj.61.715.411.
One hundred consecutive patients who had consulted their general practitioner because of upper abdominal pain related to eating, were investigated after initial interviews by the general practitioner, a medical registrar and the same consultant physician. Thirty seven had active upper gastrointestinal or biliary tract diseases, including 29 with peptic ulcers. The general practitioner and consultant correctly distinguished between organic and non-organic dyspepsia (NOD) in 51 and 65 cases respectively. Although the sensitivity of the general practitioner diagnosis of organic disease was high (95%), the specificity (23%) and predictive value (42%) were low. There were fewer organic diagnoses amongst the patients under the age of 30 (P less than 0.05) and those with symptoms for less than 3 months (P less than 0.01). No patient under 30 with symptoms for less than 3 months had organic dyspepsia. We suggest that if dyspeptic patients over the age of 30 and those under 30 with symptoms for longer than 3 months are investigated, about one-third will be found to have organic diseases.
100名因进食相关上腹部疼痛而咨询全科医生的连续患者,在经过全科医生、住院医生和同一位会诊医生的初步问诊后接受了调查。37人患有活动性上消化道或胆道疾病,其中29人患有消化性溃疡。全科医生和会诊医生分别在51例和65例中正确区分了器质性和非器质性消化不良(NOD)。尽管全科医生对器质性疾病诊断的敏感性较高(95%),但其特异性(23%)和预测值(42%)较低。30岁以下患者(P<0.05)以及症状持续时间少于3个月的患者(P<0.01)中,器质性诊断较少。30岁以下且症状持续时间少于3个月的患者中没有器质性消化不良患者。我们建议,如果对30岁以上的消化不良患者以及30岁以下且症状持续超过3个月的患者进行调查,约三分之一的患者会被发现患有器质性疾病。