Shetty Ashna, Akshatha D, Naik Shilpa A, Ranjan R K, Cutinha Freeda Praveena, Siddappa Prajwal
Department of Anesthesia, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, India.
Ann Afr Med. 2025 Oct 1;24(4):937-940. doi: 10.4103/aam.aam_243_24. Epub 2025 Apr 14.
Takayasu arteritis is an idiopathic, chronic, and inflammatory condition that mostly affects the aorta and its branches. Nearly 80% of occurrences involve females who are in their reproductive years. Although there is no effect on the disease's progression during pregnancy, these patients should be monitored for blood pressure (BP) changes and restricted intrauterine growth because they can develop complications such as hypertension, multiple organ dysfunction, and stenosis that reduces regional blood flow. Anesthetic implications of Takayasu arteritis include uncontrolled hypertension, maintenance of mean arterial pressure which is adequate to maintain end organ function, difficulty in monitoring of arterial pressure and tight maintenance of fluid regime.
A 31-year-old parturient, Gravida 3 Para 2 Living 0, hailing from north part of Karnataka, known hypertensive with previous lower segment cesarean section (LSCS) was a diagnosed case with Takayasu arteritis presented to us for elective LSCS. She had ahistory of two previous deaths of her neonate immediately following delivery. Moreover, on further evaluation was diagnosed with the above condition. Although a diagnosed case, she was never put on any treatment for the same. She was otherwise healthy carrying out her routine work without any discomfort. Her two-dimensional echo revealed severe aortic regurgitation. Rheumatology and CTVS opinion were taken. Cesarean section was planned under combined spinal epidural taking into account her clinical state and hemodynamics.
Pregnant women with Takayasu arteritis may experience an array of complications. Careful patient evaluation, treatment of TA and its complications, formulating anesthetic plan are fundamental. The key issue for these individuals is maintaining perfusion. Regional anesthesia is a safe anesthetic treatment that offers thorough preanesthetic examination and close monitoring of neurological status and BP for cesarean sections in pregnant women with Takayasu arteritis. Avoiding hemodynamic alterations and maintaining organ perfusion during the perioperative period are the most crucial objectives. To avoid postoperative complications, the patient should be monitored in an intensive care unit.
大动脉炎是一种特发性、慢性炎症性疾病,主要累及主动脉及其分支。近80%的病例发生于处于生育年龄的女性。虽然妊娠期间该病进展不受影响,但这些患者应监测血压变化及宫内生长受限情况,因为她们可能出现高血压、多器官功能障碍和导致局部血流减少的狭窄等并发症。大动脉炎的麻醉相关问题包括高血压控制不佳、维持足以维持终末器官功能的平均动脉压、动脉压监测困难以及严格维持液体平衡。
一名31岁产妇,孕3产2,0存活,来自卡纳塔克邦北部,已知患有高血压,既往有下段剖宫产史,被诊断为大动脉炎,因择期下段剖宫产前来我院就诊。她有过两次新生儿出生后即刻死亡的病史。此外,经进一步评估被诊断为上述疾病。尽管已确诊,但她从未接受过针对该疾病的任何治疗。除此之外,她身体健康,能正常进行日常工作且无任何不适。她的二维超声心动图显示严重主动脉瓣反流。已征求风湿科和心胸血管外科的意见。考虑到她的临床状况和血流动力学情况,计划在腰麻-硬膜外联合麻醉下进行剖宫产。
患有大动脉炎的孕妇可能会出现一系列并发症。仔细的患者评估、大动脉炎及其并发症的治疗、制定麻醉方案至关重要。这些患者的关键问题是维持灌注。区域麻醉是一种安全的麻醉方法,可为大动脉炎孕妇剖宫产提供全面的麻醉前检查以及对神经状态和血压的密切监测。避免围手术期血流动力学改变并维持器官灌注是最关键的目标。为避免术后并发症,患者应在重症监护病房进行监测。