Kubis A, Szust J
Pharmazie. 1985 Mar;40(3):188-91.
A mathematical model has been analyzed for the liberation process of substances (chloramphenicol) from emulsive ointments (W/O). Limitarying approximations have been derived which are useful for practical calculations. These approximations have been elaborated for the following cases: since the mass transfer resistance of diffusing substance occurs in the continuous phase, since the mass transfer resistance occurs only in the dispersed phase, then the mass transfer resistance in both phases is comparable. Experimental investigations have been carried out for the liberation process of substances from emulsive ointments. A good qualitative agreement has been found between the theoretical projections and experimental results.
对一种用于从乳剂型软膏（W/O）中释放物质（氯霉素）的数学模型进行了分析。得出了一些极限近似值，这些近似值对实际计算很有用。针对以下情况详细阐述了这些近似值：扩散物质的传质阻力发生在连续相中、传质阻力仅发生在分散相中以及两相中的传质阻力相当。对物质从乳剂型软膏中的释放过程进行了实验研究。发现理论预测与实验结果在定性上吻合良好。
