Jacob Jake Sheraj, Than Jeffrey, Tang Christine, Cano Joseph, Sheikh Rehman, Wolfson Sharon, Thrift Aaron P, Munnur Uma, Sealock Robert J
Gastroenterology, Baylor College of Medicine, Houston, United States.
Internal Medicine, Northwestern University, Evanston, United States.
Endosc Int Open. 2025 Apr 4;13:a25442468. doi: 10.1055/a-2544-2468. eCollection 2025.
Gastrointestinal debris retention (GIDR) during endoscopy can result in aborted procedures, intubation, and aspiration. GIDR has increased significance with uptake of glucagon-like peptide-1 receptor agonist (GLP-1RA) use. Outcome analysis is vital to risk-stratify patients with GIDR during endoscopy. Our study evaluated the effect of GIDR on endoscopic complications.
This was a retrospective review of patients who underwent endoscopy between May 2016 and December 2021 with documented GIDR. The study included 138 patients with GIDR and 275 controls. Propensity score matching between patients with GIDR and controls was performed in a 1:2 ratio based on age, sex, body mass index (BMI), and American Society of Anesthesiologists (ASA) status. T-tests and chi square tests were used to compare continuous and categorical variables.
The GIDR group was younger and had lower BMI, with no difference in sex, race, American Society of Anesthesiologists status, or use of monitored anesthesia care. GIDR was more frequently encountered when indications were abnormal imaging, pain, and pancreatico-biliary. Amount of GIDR was quantified as "large" in 37.7% of cases and size of debris was associated with rate of aborted procedures.
Our study did not demonstrate a significant increase in post-procedure complications in patients with GIDR. Further, the GIDR group had higher rates of opiate use, which can guide stratification of retention risk.
内镜检查期间胃肠道残渣潴留(GIDR)可导致检查中断、插管和误吸。随着胰高血糖素样肽-1受体激动剂(GLP-1RA)使用的增加,GIDR的重要性日益凸显。结果分析对于内镜检查期间GIDR患者的风险分层至关重要。我们的研究评估了GIDR对内镜并发症的影响。
这是一项对2016年5月至2021年12月期间接受内镜检查且有GIDR记录患者的回顾性研究。该研究纳入了138例GIDR患者和275例对照。基于年龄、性别、体重指数(BMI)和美国麻醉医师协会(ASA)分级,对GIDR患者与对照进行了1:2比例的倾向评分匹配。采用t检验和卡方检验比较连续变量和分类变量。
GIDR组患者更年轻,BMI更低,在性别、种族、美国麻醉医师协会分级或监护麻醉护理的使用方面无差异。当适应证为异常影像、疼痛和胰胆疾病时,GIDR更为常见。37.7%的病例中GIDR量被量化为“大量”,残渣大小与检查中断率相关。
我们的研究未显示GIDR患者术后并发症有显著增加。此外,GIDR组阿片类药物使用率更高,这可指导对潴留风险进行分层。