Knox-Brown Ben, Harding Chris, Chowdhury Shabana, Pritchard Andrew, Shakespeare Joanna, Sylvester Karl Peter
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
BMJ Open Respir Res. 2025 Apr 15;12(1):e002824. doi: 10.1136/bmjresp-2024-002824.
The impact of cycling at different cadences on cardiopulmonary exercise test (CPET) measurements is poorly understood. We aimed to investigate whether higher cadences of pedalling led to meaningful changes in physiological endpoints.
Study participants were recruited from healthy staff members working within three NHS trusts across England. At baseline, all participants completed a CPET at 60 rpm and then subsequently completed CPETs at cadences of 70, 80 and 90 rpm, allocated in a random order. To evaluate the mean differences in CPET measurements across the cadences, we used a one-way repeated measures analysis of variance. We then performed post hoc pairwise comparisons with Tukey correction to account for multiple testing.
Data collection took place between the 19 September 2023 and 9 April 2024. 25 participants had complete data at each cadence. 48% (12 of 25) were female, with a median (IQR) age of 30 years (27-41). There was no significant difference in peak V̇O across the cadences. Maximum achieved work rate was significantly different across the cadences (p=<0.001). The highest wattage was achieved at 60 rpm (221.2 watts±71.4) and lowest at 90 rpm (210.4 watts, ±77.2). End exercise ventilation increased with increasing cadence (p=0.013), with a mean of 97.6 L/min (±28.3) at 60 prm and 107.0 L/min (±33.9) at 90 prm. Breathing reserve decreased with increasing cadence (p=0.009), with a mean of 45.6 L/min (±28.8) at 60 rpm and 35.1 L/min (±23.5) at 90 rpm. There were minimal differences in other CPET parameters.
In a healthy population, higher cycling cadences increased ventilatory demand and reduced maximum work rate. This could have implications for CPETs in the clinical setting, where physiological responses to higher cadences may be more exaggerated.
不同踏频骑行对心肺运动试验（CPET）测量结果的影响尚不清楚。我们旨在研究更高的踏频是否会导致生理终点指标发生有意义的变化。
研究参与者从英格兰三个国民保健服务信托机构的健康工作人员中招募。在基线时，所有参与者以60转/分钟的速度完成一次CPET，然后随后以70、80和90转/分钟的踏频完成CPET，顺序随机分配。为了评估不同踏频下CPET测量结果的平均差异，我们使用了单向重复测量方差分析。然后，我们进行了事后两两比较，并采用Tukey校正以考虑多重检验。
数据收集于2023年9月19日至2024年4月9日期间进行。25名参与者在每个踏频下都有完整的数据。48%（25人中的12人）为女性，年龄中位数（IQR）为30岁（27 - 41岁）。不同踏频下的峰值摄氧量没有显著差异。不同踏频下达到的最大工作率有显著差异（p = <0.001）。最高功率在60转/分钟时达到（221.2瓦±71.4），在90转/分钟时最低（210.4瓦，±77.2）。运动结束时的通气量随踏频增加而增加（p = 0.013），60转/分钟时平均为97.6升/分钟（±28.3），90转/分钟时为107.0升/分钟（±33.9）。呼吸储备随踏频增加而降低（p = 0.009），60转/分钟时平均为45.6升/分钟（±28.8），90转/分钟时为35.1升/分钟（±23.5）。其他CPET参数的差异最小。
在健康人群中，更高的骑行踏频会增加通气需求并降低最大工作率。这可能对临床环境中的CPET产生影响，在临床环境中，对更高踏频的生理反应可能会更加夸张。
