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高剂量布地奈德治疗的哮喘患者的肾上腺功能。

Adrenal function in asthmatics treated with high-dose budesonide.

作者信息

Stiksa G, Nemcek K, Glennow C

出版信息

Respiration. 1985;48(1):91-3. doi: 10.1159/000194805.

DOI:10.1159/000194805
PMID:4023443
Abstract

Plasma cortisol concentrations have been measured in 14 asthmatics previously treated with oral steroids in addition to conventional doses of beclomethasone dipropionate. Three months after switching over to budesonide in a dose of 800 micrograms twice daily, oral steroid intake has been reduced and a return of the initially depressed adrenal function has been achieved.

摘要

对14名哮喘患者的血浆皮质醇浓度进行了测量,这些患者之前除了常规剂量的二丙酸倍氯米松外还接受了口服类固醇治疗。在转换为每日两次、剂量为800微克的布地奈德三个月后,口服类固醇的摄入量减少,并且最初受抑制的肾上腺功能已恢复。

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Adrenal function in asthmatics treated with high-dose budesonide.高剂量布地奈德治疗的哮喘患者的肾上腺功能。
Respiration. 1985;48(1):91-3. doi: 10.1159/000194805.
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Equally efficacious asthma management with budesonide 800 micrograms administered by Turbuhaler or with beclomethasone dipropionate > or = 1500 micrograms given through a pressurized metered-dose inhaler with spacer. The French Budesonide Trial Group.使用都保装置吸入800微克布地奈德与使用带储雾罐的压力定量气雾剂吸入≥1500微克二丙酸倍氯米松在哮喘管理方面疗效相当。法国布地奈德试验组。
Adv Ther. 1996 Jan-Feb;13(1):38-50.
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Comparison of budesonide and beclomethasone dipropionate for treatment of asthma.布地奈德与丙酸倍氯米松治疗哮喘的比较。
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Budesonide inhaled via Turbuhaler: a more effective treatment for asthma than beclomethasone dipropionate via Rotahaler.通过都保吸入布地奈德:一种比通过准纳器吸入二丙酸倍氯米松更有效的哮喘治疗方法。
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Four-times-a-day dosing frequency is better than a twice-a-day regimen in subjects requiring a high-dose inhaled steroid, budesonide, to control moderate to severe asthma.对于需要高剂量吸入性类固醇布地奈德来控制中重度哮喘的患者,每日四次给药频率优于每日两次的治疗方案。
Am Rev Respir Dis. 1989 Sep;140(3):624-8. doi: 10.1164/ajrccm/140.3.624.

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