住院癌症患者中由气单胞菌属引起的菌血症。

Bacteremia caused by Aeromonas species in hospitalized cancer patients.

作者信息

Harris R L, Fainstein V, Elting L, Hopfer R L, Bodey G P

出版信息

Rev Infect Dis. 1985 May-Jun;7(3):314-20. doi: 10.1093/clinids/7.3.314.

DOI:10.1093/clinids/7.3.314

Abstract

Bacteremia caused by Aeromonas species occurred in 24 hospitalized patients in a cancer institute during a 13-year period. All but one of these patients had a malignancy (88% had leukemia), and most were receiving chemotherapy for cancer. There was a striking numerical predominance of male patients (82%). Unlike some previously described patients with infections due to this organism, none of these 24 patients had recently been exposed to fresh or salt water or to fish. The source of the infecting organism was thought to be endogenous--i.e., from patients' own gastrointestinal tracts. The clinical presentation of sepsis caused by this organism was nonspecific, except that ecthyma gangrenosum occurred in several patients. The overall mortality rate was 28%. The combination of an aminoglycoside and a cephalosporin is appropriate therapy for bacteremia caused by Aeromonas species.

摘要

在13年期间，一家癌症研究所的24名住院患者发生了气单胞菌属菌血症。除1名患者外，所有这些患者均患有恶性肿瘤（88%患有白血病），且大多数正在接受癌症化疗。男性患者在数量上占显著优势（82%）。与之前描述的一些感染该病原体的患者不同，这24名患者中没有一人近期接触过淡水、盐水或鱼类。感染源被认为是内源性的，即来自患者自身的胃肠道。该病原体引起的败血症临床表现不具特异性，不过有几名患者出现了坏疽性脓皮病。总体死亡率为28%。氨基糖苷类药物和头孢菌素联合使用是治疗气单胞菌属菌血症的合适疗法。