新型哌啶基吡啶基甲腈衍生物作为治疗癌症的QPCT和QPCTL抑制剂
Novel Piperidinylpyridinylcarbonitrile Derivatives as QPCT and QPCTL Inhibitors for Treating Cancer.
作者信息
Sabnis Ram W
机构信息
Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Atlanta, Georgia 30309, United States.
出版信息
ACS Med Chem Lett. 2025 Apr 2;16(4):540-541. doi: 10.1021/acsmedchemlett.5c00142. eCollection 2025 Apr 10.
Abstract
Provided herein are novel piperidinylpyridinylcarbonitrile derivatives as QPCT and QPCTL inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds.
摘要
本文提供了作为QPCT和QPCTL抑制剂的新型哌啶基吡啶基甲腈衍生物、药物组合物、此类化合物在治疗癌症中的用途以及制备此类化合物的方法。
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