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慢性牙周炎患者中臭氧水与生理盐水冲洗联合机械清创的比较评估——一项临床研究

Comparative evaluation of ozonized water versus normal saline irrigation with mechanical debridement in chronic periodontitis patients - A clinical study.

作者信息

Rohith G N, Patel Nayana, Jha Rita, Vachhani Radha, Verlianey Nisha, Sant Ankit

机构信息

Department of Periodontology and Implantology, Government Dental College and Hospital, Jamnagar, India.

Department of Oral Medicine and Radiology, Government Dental College and Hospital, Jamnagar, India.

出版信息

J Oral Biol Craniofac Res. 2025 May-Jun;15(3):594-599. doi: 10.1016/j.jobcr.2025.03.014. Epub 2025 Mar 31.

Abstract

BACKGROUND

Ozone therapy is a rather novel approach for managing many diseases, encompassing oral disorders such as tooth caries and periodontal disease. It possesses the ability to disrupt microbial cell walls, resulting in rapid cell lysis. Moreover, characteristics of ozone such as anti-inflammation, stimulation and modulation of immunity contribute to mitigating the host response aspect of periodontal disease.

OBJECTIVE

To assess the adjunctive advantages of irrigation of ozonized water in conjunction with mechanical debridement for the treatment of periodontitis.

METHODOLOGY

50 patients with chronic periodontitis and pocket probing depth ≥4 have been divided into 2 groups i.e. Test (n = 25) and control groups (n = 25). While the control group was administered normal saline irrigation and mechanical debridement, the test group was given ozonized water irrigation. Evaluations were conducted at baseline and four weeks following treatment to determine the plaque score, bleeding score, pocket probing depth, and clinical attachment level.

RESULTS

Clinical measures such as clinical attachment level, pocket probing depth, bleeding index, and plaque index, significantly improved with adjunctive ozone water irrigation. The frequency of sites with bleeding on probing that had a pocket depth ≥4 mm was significantly reduced as a result of ozone water irrigation.

CONCLUSION

Ozone irrigation alongside nonsurgical periodontal therapy offers adjunctive benefits by reducing clinical parameters.

摘要

背景

臭氧疗法是一种治疗多种疾病的相当新颖的方法,包括龋齿和牙周病等口腔疾病。它具有破坏微生物细胞壁的能力,导致细胞快速裂解。此外,臭氧的抗炎、刺激和调节免疫等特性有助于减轻牙周病的宿主反应。

目的

评估臭氧水冲洗联合机械清创治疗牙周炎的辅助优势。

方法

将50例慢性牙周炎且牙周袋探诊深度≥4mm的患者分为2组,即试验组(n = 25)和对照组(n = 25)。对照组采用生理盐水冲洗和机械清创,试验组采用臭氧水冲洗。在基线和治疗后4周进行评估,以确定菌斑评分、出血评分、牙周袋探诊深度和临床附着水平。

结果

临床附着水平、牙周袋探诊深度、出血指数和菌斑指数等临床指标在辅助臭氧水冲洗后有显著改善。由于臭氧水冲洗,牙周袋深度≥4mm的探诊出血部位的频率显著降低。

结论

臭氧冲洗联合非手术牙周治疗通过降低临床参数提供辅助益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d96d/11999260/0ed16072c739/gr1.jpg

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