Wang Xiaojing, Zhou Ping, Hu Xiaoyu, Bai Yun, Zhang Chenhao, Fu Yanhong, Huang Ruirui, Suzhen Niu, Song Xiaoming
Institute of Agro-Bioengineering/The Key Laboratory of Plant Resources Conservation and Germplasm Innovation in the Mountainous Region (Ministry of Education)/College of Life Sciences Guizhou University Guiyang China.
School of Life Sciences/School of Basic Medical Sciences North China University of Science and Technology Tangshan China.
Imeta. 2025 Mar 5;4(2):e70010. doi: 10.1002/imt2.70010. eCollection 2025 Apr.
This study reports the first high-quality telomere-to-telomere (T2T) genome with 11 chromosomes that are gap free. The 24 telomeres and all 13 centromeres detected in this genome, which reached the highest quality gold level. In addition, other three species were sequenced and assembled to the chromosomal level. Based on 15 genomes, we conducted a pan-genome analysis of genus . Combining the genome and whole transcriptome sequencing, we identified several key genes and miRNAs related to the heat stress, which were further verified by transgenic experiments. Our findings provide rich resources for comparative and functional genomics studies of species.
本研究报告了首个高质量的端粒到端粒（T2T）基因组，该基因组包含11条无间隙的染色体。在这个达到最高质量金标准的基因组中检测到了24个端粒和所有13个着丝粒。此外，还对其他三个物种进行了测序并组装到染色体水平。基于15个基因组，我们对该属进行了泛基因组分析。结合基因组和全转录组测序，我们鉴定了几个与热应激相关的关键基因和微小RNA（miRNA），并通过转基因实验进一步验证。我们的研究结果为该物种的比较和功能基因组学研究提供了丰富的资源。
