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中国糖尿病患者抑郁症状的患病率及相关因素:一项基于安德森行为模型的研究

Prevalence and associated factors of depressive symptoms in Chinese diabetic patients: A study based on Andersen's behavioral model.

作者信息

Xiao Wen-Hui, Yang Xiao-Cong, Xu Si-Jie, Bian Ying, Zou Guan-Yang

机构信息

School of Public Health and Management, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong Province, China.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China.

出版信息

World J Diabetes. 2025 Apr 15;16(4):100638. doi: 10.4239/wjd.v16.i4.100638.

Abstract

BACKGROUND

Diabetes mellitus (DM) is a rapidly growing global health emergency of the 21 century. Comorbidities, such as DM and depression, are common, presenting challenges to the healthcare system.

AIM

To investigate the prevalence of depression and its associated factors in patients with DM and to strengthen the management of depression in this patient group.

METHODS

Participants were selected from the 2018 China Health and Retirement Longitudinal Study. Depressive symptoms were assessed using the 10-item Center for Epidemiological Studies Depression Scale, with a score of 10 or more indicating depression. Group differences were compared using analysis of variance and tests. Binary logistic regression was conducted to explore the odds ratios (ORs) of independent variables. Following Andersen's behavioral model, predisposing, enabling, health need, and health behavior variables were introduced stepwise into the logistic model.

RESULTS

Of the 1673 patients with diabetes, 41.4% had depressive symptoms. Regarding the predisposing characteristics, patients who were male (OR 0.426, < 0.05), married (OR 0.634, < 0.05), and received a high school education or higher (OR 0.432, < 0.05) reported fewer depressive symptoms. Healthcare needs, including better self-rated health (OR 0.458 for fair and OR 0.247 for good, < 0.05) and more sleep (OR 0.642, < 0.05), were associated with a lower likelihood of depressive symptoms. In contrast, pain (OR 1.440 for mild and OR 2.644 for severe, < 0.05) and impairment in the basic activities of daily living (OR 1.886, < 0.05) were inversely associated. Additionally, patients highly satisfied with healthcare services (OR 0.579, < 0.05) were less likely to have depressive symptoms.

CONCLUSION

Nearly half of the patients with DM reported depressive symptoms, which were strongly associated with predisposing characteristics and healthcare needs, particularly physical pain and impairment in basic activities of daily living. Our study emphasizes the significance of enhanced screening and intervention for depression in diabetes care along with improved management of functional impairments.

摘要

背景

糖尿病(DM)是21世纪全球迅速增长的重大健康问题。糖尿病和抑郁症等合并症很常见,给医疗系统带来了挑战。

目的

调查糖尿病患者中抑郁症的患病率及其相关因素,并加强对该患者群体抑郁症的管理。

方法

参与者选自2018年中国健康与养老追踪调查。使用10项流行病学研究中心抑郁量表评估抑郁症状,得分10分及以上表明患有抑郁症。采用方差分析和检验比较组间差异。进行二元逻辑回归以探索自变量的比值比(OR)。按照安德森行为模型,将 predisposing、 enabling、健康需求和健康行为变量逐步引入逻辑模型。

结果

在1673名糖尿病患者中,41.4%有抑郁症状。关于 predisposing特征,男性患者(OR 0.426,<0.05)、已婚患者(OR 0.634,<0.05)以及接受过高中及以上教育的患者(OR 0.432,<0.05)报告的抑郁症状较少。健康需求,包括自我评估健康状况较好(一般健康状况的OR为0.458,良好健康状况的OR为0.247,<0.05)和睡眠较多(OR 0.642,<0.05),与抑郁症状发生可能性较低相关。相比之下,疼痛(轻度疼痛的OR为1.440,重度疼痛的OR为2.644,<0.05)和日常生活基本活动能力受损(OR 1.886,<0.05)与之呈负相关。此外,对医疗服务高度满意的患者(OR 0.579,<0.05)出现抑郁症状的可能性较小。

结论

近一半的糖尿病患者报告有抑郁症状,这些症状与 predisposing特征和健康需求密切相关,尤其是身体疼痛和日常生活基本活动能力受损。我们的研究强调了在糖尿病护理中加强抑郁症筛查和干预以及改善功能障碍管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d4/11947904/9dbd92751dbc/100638-g001.jpg

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