The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital & the Advanced Innovation Center for Human Brain Protection, Capital Medical University, Xicheng District, Beijing, China.
School of Nursing, Capital Medical University, Beijing, China.
Psychiatr Q. 2019 Dec;90(4):883-895. doi: 10.1007/s11126-019-09666-9.
Major depressive disorder (MDD) is a common psychiatric disorder in China, but its reported treatment rate varies largely across different studies. The objective of this meta-analysis was to determine the pooled treatment rate for people with MDD in China and its associated factors. Both English (PubMed, Cochrane Library, PsycINFO, Web of Science) and Chinese (Chinese National Knowledge Infrastructure, WanFang and SinoMed) databases were searched from their commencement date to November 13, 2018. Epidemiological studies that reported the treatment rate of MDD were included and synthesized using a random effects model. Fifteen studies covering 609,054 participants were included. The pooled treatment rate for MDD in China was 19.5% (95% CI: 10.7%-28.4%). Among the 15 studies, 9 reported the number of patients who received treatments in psychiatric hospitals with a pooled treatment rate of 5.2% (95% CI: 2.8%-7.5%). Meta-regression found that study quality (β = 0.131, P = 0.028) and male gender (β = 0.006, P = 0.039) were significantly associated with a higher treatment rate for MDD. In China, the treatment rate for MDD, particularly in psychiatric hospitals, was low. Effective public education and increasing access to mental health services will probably increase the number of people seeking and receiving treatment.
重度抑郁症（MDD）是中国常见的精神障碍，但不同研究报道的治疗率差异较大。本荟萃分析旨在确定中国 MDD 患者的治疗率及其相关因素。检索了英文数据库（PubMed、Cochrane Library、PsycINFO、Web of Science）和中文数据库（中国知网、万方和中国生物医学文献数据库），检索时间从建库至 2018 年 11 月 13 日。纳入报道 MDD 治疗率的流行病学研究，采用随机效应模型进行综合。共纳入 15 项研究，涵盖 609054 名参与者。中国 MDD 的治疗率为 19.5%（95%CI：10.7%-28.4%）。在这 15 项研究中，有 9 项报道了在精神病院接受治疗的患者数量，治疗率为 5.2%（95%CI：2.8%-7.5%）。Meta 回归发现，研究质量（β=0.131，P=0.028）和男性性别（β=0.006，P=0.039）与 MDD 的较高治疗率显著相关。在中国，MDD 的治疗率，尤其是在精神病院，较低。有效的公众教育和增加获得心理健康服务的机会可能会增加寻求和接受治疗的人数。
