Yodbutra S, Ketavan C, Upatham E S, Areekul S
Southeast Asian J Trop Med Public Health. 1985 Mar;16(1):41-8.
Effects of 2-methyl-9(4-isopropylphenyl)-2,6-dimethyl nonane, or MV-678, a juvenile hormone analogue, on Aedes scutellaris malayensis Colless were investigated under laboratory conditions (29 degrees +/- 2 degrees C and 86 +/- 3% RH). The MV-678 was tested against the first, second, third and fourth instar larvae. The concentrations used were 0.0032, 0.016, 0.08, 0.4 and 2.0 mg/l. The morphogenetic aberrations were determined and divided into 8 groups, among which they included (1) death larvae, (2) late fourth instar larvae before pupation, (3) larvae with pupae partly emerged, (4) white pupae, (5) brown pupae, (6) elephantoid pupae of which pupae with adults visible inside, (7) pupae with apparently adults partly emerged and (8) death adults. The percentage mortality rates were found to be relatively high in pupal and larval stages when they were treated with 2.0 mg/l. The LC50 values were 0.26, 0.175, 0.06 and 0.032 mg/l for the first, second, third and fourth instar larvae respectively. The effectiveness of MV-678 at 2.0 mg/l was about 11 days under the open air conditions (28 degrees +/- 2 degrees C and 72 +/- 3% RH). When the fourth instar larvae were treated with 0.4 and 2.0 mg/l of MV-678, the LC50 values were 3.1 and 7.1 days respectively.
在实验室条件（29摄氏度±2摄氏度，相对湿度86%±3%）下，研究了保幼激素类似物2-甲基-9（4-异丙基苯基）-2,6-二甲基壬烷（MV-678）对斯氏伊蚊马来亚种（Colless）的影响。MV-678针对伊蚊的一龄、二龄、三龄和四龄幼虫进行了测试。使用的浓度分别为0.0032、0.016、0.08、0.4和2.0毫克/升。测定了形态发生畸变情况，并将其分为8组，其中包括：（1）死亡幼虫；（2）化蛹前的晚期四龄幼虫；（3）部分羽化出蛹的幼虫；（4）白色蛹；（5）棕色蛹；（6）象鼻状蛹（蛹内可见成虫）；（7）部分成虫明显羽化出的蛹；（8）死亡成虫。当用2.0毫克/升处理时，发现蛹期和幼虫期的死亡率相对较高。一龄、二龄、三龄和四龄幼虫的半数致死浓度（LC50）值分别为0.26、0.175、0.06和0.032毫克/升。在露天条件（28摄氏度±2摄氏度，相对湿度72%±3%）下，2.0毫克/升的MV-678有效期约为11天。当用0.4和2.0毫克/升的MV-678处理四龄幼虫时，其半数致死浓度值分别为3.1天和7.1天。
